Evidence map›Paper›PMID 39707422›Full record

ArticleJournal of nanobiotechnology2024

Resistant starch grafted cerium-sulfasalazine infinite coordination polymers synergistically remold intestinal metabolic microenvironment for inflammatory bowel disease therapy.

Jing Zhang, Liyuan Zhao, Along Liang, Xueyan Geng, Mengmeng Hou, Haojie Cheng, Shouren Zhang, Baocheng Yang, Junbo Li, Jian Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing ZhangSchool of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang, 471023, China.
Liyuan ZhaoSchool of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang, 471023, China.
Along LiangHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China.
Xueyan GengHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China.
Mengmeng HouHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China.
Haojie ChengHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China.
Shouren ZhangHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China.
Baocheng YangHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China. baochengyang@infm.hhstu.edu.cn.
Junbo LiSchool of Chemistry and Chemical Engineering, Henan University of Science and Technology, Luoyang, 471023, China. Lijunbo@haust.edu.cn.
Jian ChenHenan Key Laboratory of Nanocomposite and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College, Zhengzhou, 450006, Henan, China. jianchen@infm.hhstu.edu.cn.

Funding

National Natural Science Foundation of China 51902123National Natural Science Foundation of China-Henan Joint Fund U1704150Natural Science Foundation of Henan Province 222102310155Natural Science Foundation of Henan Province 23230042014Postgraduate Education Reform and Quality Improvement Project of Henan Province YJS2022JD50
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease which is closely related with the overproduced reactive oxygen species (ROS), increased pro-inflammatory cytokines and disordered intestinal microbes. However, current therapeutic methods usually ignored the interrelation among the pathogenesis, and mainly focused on a single factor, inducing clinical outcomes unsatisfied. Herein, biocompatible infinite coordination polymers of drugs (Ce-SASP-RS ICPs) composed of Ce ions, FDA-approved drug sulfasalazine (SASP) and natural ingredient resistant starch (RS) were developed for synergistic treatment of IBD. The proper Ce

Indexed as

CeriumGastrointestinal MicrobiomeInflammatory Bowel DiseasesReactive Oxygen SpeciesSulfasalazineAnimalsAnti-Inflammatory AgentsHumansIntestinesMaleMiceMice, Inbred C57BLPolymersResistant StarchStarchAnti-Inflammatory AgentsCeriumPolymersReactive Oxygen SpeciesResistant StarchStarchSulfasalazineAnti-inflammationInfinite coordination polymersInflammatory bowel diseaseIntestinal flora regulationRedox balance

Identifiers

PMID39707422
PMCPMC11662453

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.