SynthesisJournal of cardiothoracic surgery2024
Risk factors of delirium after cardiac surgery: a systematic review and meta-analysis.
Synthesis in Journal of cardiothoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing sugammadex to neostigmine and their effects on delirium and postoperative cognitive function: A systematic review.Journal of perioperative practice · 2026Pooled it
- Effect of desflurane versus propofol on perioperative neurocognitive disorders in older adults undergoing major urological surgery: a randomized trial.BMC geriatrics · 2026Trial
- Incidence and risk factors for delirium in cardiac surgery intensive care unit patients: A single-center study.World journal of critical care medicine · 2026Article
- Blood-Based Versus Crystalloid Cardiopulmonary Bypass Priming in Left Ventricular Assist Device Surgery: Impact on End-Organ Function and Survival.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Validation of intraoperative processed electroencephalography and cerebral oximetry for prediction of postoperative delirium in cardiac surgery: a prospective observational study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Observational
- Delirium after coronary artery bypass grafting with cardiopulmonary bypass surgery: The value of cerebral autoregulation.Perfusion · 2026Article
- Preoperative frontal lobe and global cognitive function as predictors of postoperative delirium after cardiovascular surgery: a predictive and exploratory mediation analysis.Heart and vessels · 2026Article
- Preoperative frontal EEG power spectral features associated with psychomotor subtypes of postoperative delirium in cardiovascular surgery: a prospective study.Scientific reports · 2026Article
- Article
- Postoperative Delirium After Coronary Artery Bypass Grafting in the United States, 2016-2021: Trends, Risk Factors, and Outcomes.Journal of cardiothoracic and vascular anesthesia · 2026Observational
- Postoperative diastolic perfusion pressure as a predictor of delirium after cardiac surgery.Frontiers in cardiovascular medicine · 2026Article
- Delirium after surgery: a retrospective study of predictors, complications, and screening patterns in the national surgical quality improvement program.EClinicalMedicine · 2025Article
- Article
- What is new in cardiac anesthesia in 2024?Journal of anesthesia and translational medicine · 2025Review
- Analyzing Key Predictors of Postoperative Delirium Following Coronary Artery Bypass Grafting and Aortic Valve Replacement: A Machine Learning Perspective.Medicina (Kaunas, Lithuania) · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-operative delirium (POD) is a relatively common occurrence following surgical procedures, particularly cardiac surgeries. Given that the majority of pharmacologic treatments for delirium have demonstrated inadequate efficacy, it is of great importance to identify risk factors to prevent delirium or reduce its complications. Consequently, in this systematic review and meta-analysis, we identified risk factors of POD after cardiac surgery.
methodA comprehensive search of the literature was conducted using the databases Scopus, PubMed, and Web of Science from the inception to April 22, 2024. The objective was to identify prospective cohorts that had assessed the risk factors associated with POD in patients undergoing cardiac surgery using multivariate regression.
resultsOf the 3,166 studies that were initially screened, 23 were included in the review. Nine risk factors were evaluated including age (OR 1.06, 95% CI (1.04, 1.08), p < 0.001), pre-operative depression (OR 3.71, 95% CI (2.45, 5.62), p < 0.001), post-operative atrial fibrillation (AF) (OR 2.39, 95% CI (1.79, 3.21), p < 0.001), hypertension (HTN) (OR 1.64, 95% CI (0.75, 3.56), p = 0.212), age ≥ 65 (OR 3.32, 95% CI (2.40, 4.60), p < 0.001), pre-operative AF (OR 4.43, 95% CI (2.56, 7.69), p < 0.001), diabetes mellitus (OR 2.16, 95% CI (1.39, 3.35), p = 0.001), combined coronary artery bypass graft (CABG) + valve surgery (OR 2.73, 95% CI (1.66, 4.49), p < 0.001), and cardiopulmonary bypass (CPB) time (OR 1.02, 95% CI (1.01, 1.04), p = 0.001).
conclusionsA total of nine risk factors were evaluated, from which eight were found to have a statistically significant effect on the risk of developing POD. These factors can be employed to more effectively identify at-risk patients and to prevent the occurrence of POD. Furthermore, this approach can facilitate earlier diagnosis and more effective patient care.
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