ArticleGeroScience2025
Association of the interaction between daily step counts and frailty with disability in older adults.
Article in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effectiveness of nudge-based physical activity interventions in frail older adults: a systematic review.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- Association between daily step counts and frailty trajectory classes in lung cancer patients undergoing radiotherapy: a prospective longitudinal study.Journal of cancer survivorship : research and practice · 2026Article
- Real-world walking speed as a digital biomarker and outcome measure for clinical trials-a systematic review, regulatory status and future directions.Frontiers in digital health · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The differences in the association of objectively measured physical activity with disability between frail and non-frail older adults remain unclear. We (1) evaluated the dose-dependent relationship between daily steps and disability in older adults with and without frailty and (2) examined the interaction between steps and frailty status in relation to the risk of disability. This prospective study used data from 4065 adults aged ≥ 65 years from the Kyoto-Kameoka Study, Japan. The mean daily step count obtained using triaxial accelerometers across ≥ 4 days was recorded. Frailty was evaluated using the validated Kihon Checklist. Disability was identified using the long-term care insurance system's nationally unified database, with data collected until November 30, 2016. Overall, 385 disabilities were recorded during a median follow-up period of 3.32 years (12,855 person-years). After adjusting for confounders, an inverse association was observed between daily step count and disability risk. The disability risk plateaued at 5,000-7,000 steps/day in non-frail people, whereas step counts showed an almost linear inverse relationship with disability risk in frail people. Low step counts (< 5,000 steps) in frail people were more strongly associated with disability risk than were high step counts (≥ 5,000 steps) in non-frail people. The additive interaction between steps and frailty was associated with the relative excess risk of disability in frail people with low step counts (p for interaction = 0.015). The relationship between daily steps and disability differs between older adults with and without frailty, and the adverse effects of frailty on disability risk depend on physical activity.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.