Evidence map›Paper›PMID 39711223›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2025

Deleterious impacts of Western diet on jejunum function and health are reversible.

Sarah Carpinelli, John Ahlert, Maxwell Rubin, Alex Aratani, Emma Smith, Dana Floyd, Ross M Potter, Layla Al-Nakkash

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Hope for the gut: new evidence suggests Western diet damage can be undone.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Sarah CarpinelliArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, United States.
John AhlertArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, United States.
Maxwell RubinArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, United States.
Alex ArataniArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, United States.
Emma SmithCollege of Veterinary Medicine, Midwestern University, Glendale, Arizona, United States.
Dana FloydDepartment of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Arizona, United States.
Ross M PotterDepartment of Physiology, College of Graduate Studies, Midwestern University, Glendale, Arizona, United States.
Layla Al-NakkashArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, United States.ORCID 0000-0001-9309-6213

Funding

Diabetes Action Research and Education Foundation (DAREF) AZ0221Midwestern Arizona Alzheimer's Assocaition AZ21-0021Midwestern University (MWU)
6 · The paper itself

Abstract

The goal of this study was to determine whether the influence of a high-fat high-sugar diet (Western diet) on intestinal function and health was reversible. We measured transepithelial short circuit current (

Indexed as

Diet, High-FatDiet, WesternJejunumAnimalsIntestinal MucosaMaleMiceMice, Inbred C57BLObesityTumor Necrosis Factor-alphaTumor Necrosis Factor-alphahigh-fat dietintestinal healthmorphologytransporters

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.