Evidence map›Paper›PMID 39711266›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Differential associations of neighborhood disadvantage, race/ethnicity, and cognitive status with experiences of psychosocial distress in the HABS-HD cohort.

Tasha Rhoads, Christina G Wong, Kimberly Cobos, Sid E O'Bryant, Amy J H Kind, Justin B Miller, Health and Aging Brain Study (HABS‐HD) Team

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Multimorbidity, Polypharmacy, and Neighborhood Disadvantage as Determinants of Cognitive Performance in the ARCHES Cohort.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  2. Article
  3. Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Observational
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tasha RhoadsNeurological Institute, Section of Neuropsychology, Cleveland Clinic, Cleveland, Ohio, USA.ORCID 0000-0001-9708-0083
Christina G WongLou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, Nevada, USA.ORCID 0000-0002-7107-5267
Kimberly CobosLou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, Nevada, USA.
Sid E O'BryantInstitute for Translational Research, University of North Texas Health Science Center, Fort Worth, Texas, USA.ORCID 0000-0003-0582-5266
Amy J H KindCenter for Health Disparities Research, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-7183-610X
Justin B MillerLou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, Nevada, USA.ORCID 0000-0002-4439-6604
Health and Aging Brain Study (HABS‐HD) Team

Funding

The Health & Aging Brain Study - Health Disparities (HABS-HD)U19AG078109 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI LEIGH A JOHNSON · 2022 to 2026
$181.1M
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyR01AG058533 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI JOHNSON, LEIGH A, O'BRYANT, SID E · 2020 to 2025
$45.4M
The Neighborhoods Study: Contextual Disadvantage and Alzheimer’s Disease and Related Dementias (ADRD)R01AG070883 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI AMY J. KIND · 2021 to 2026
$42.1M
Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI Robert J. Fox, Jefferson Kinney · 2015 to 2026
$22.8M
ALZHEIMERS DISEASE PREVENTION TRIAL WITH ESTROGENSR01AG015922 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SANO, MARY · 1998 to 2007
$14.6M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOGA, ARTHUR W · 2012 to 2022
$14.1M
Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican AmericansR01AG054073 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI O'BRYANT, SID E, TOGA, ARTHUR W · 2017 to 2021
$12.6M
Neighborhood Socioeconomic Contextual Disadvantage and Alzheimer's DiseaseRF1AG057784 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI BENDLIN, BARBARA BRIGITTA, KIND, AMY J. · 2017 to 2017
$3.8M
NVEDARC Clinical CoreP20AG068053 · NIA · CLEVELAND CLINIC FOUNDATION · PI FOX, ROBERT J. · 2020 to 2022
$3.3M
ADI and Neighborhood Atlas R01AG070883ADI and Neighborhood Atlas RF1AG057784National Institute on Aging of the National Institutes of Health P41EB015922National Institute on Aging of the National Institutes of Health R01AG054073National Institute on Aging of the National Institutes of Health R01AG058533National Institute on Aging of the National Institutes of Health U19AG078109NIA NIH HHS P20 AG068053NIA NIH HHS R01 AG054073NIA NIH HHS R01 AG058533NIA NIH HHS R01 AG070883NIA NIH HHS RF1 AG057784NIA NIH HHS U19 AG078109NIBIB NIH HHS P41 EB015922NIGMS NIH HHS P20 GM109025
6 · The paper itself

Abstract

introductionUnderstanding how contextual socioeconomic factors are associated with psychosocial distress among different ethnoracial groups is important for addressing health disparities in individuals at risk for Alzheimer's disease.

methodsUsing Health and Aging Brain Study-Health Disparities (HABS-HD) data collected between 2017 and 2023, we examined the association of neighborhood disadvantage with psychosocial distress using demographically adjusted linear regression models, stratified by ethnoracial group and cognitive status.

resultsWe included 630 non-Hispanic Black, 1109 Hispanic, and 1068 non-Hispanic White older adults deemed cognitively normal (CN) or diagnosed with mild cognitive impairment (MCI). Residing in areas of greater neighborhood disadvantage was associated with increased chronic stress (CS) among CN White participants, but this relationship was attenuated among White participants with MCI. Regardless of cognitive status, severe levels of disadvantage were associated with increased CS and depression among Black participants. DISCUSSION: Aging in more disadvantaged neighborhoods was associated with greater CS and depression for Black and White participants. HIGHLIGHTS: Greater neighborhood disadvantage was associated with increased depression and chronic stress for White and Black individuals. Individuals with mild cognitive impairment reported greater levels of psychosocial distress. These findings are relevant for addressing mental health inequity in aging populations.

Indexed as

Cognitive DysfunctionHealth Status DisparitiesHispanic or LatinoNeighborhood CharacteristicsPsychological DistressRacial GroupsStress, PsychologicalAgedAged, 80 and overBlack or African AmericanCognitionCohort StudiesDepressionFemaleHumansMaleaginganxietychronic stressdepressionmental healthneighborhood disadvantage

Identifiers

PMID39711266
PMCPMC11772701

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.