Evidence map›Paper›PMID 39711771›Full record

ArticleInternational journal of cardiology. Congenital heart disease2024

Diagnosis and management of peripartum cardiomyopathy and recurrence risk.

Giulia Iannaccone, Francesca Graziani, Polona Kacar, Pietro Paolo Tamborrino, Rosa Lillo, Claudia Montanaro, Francesco Burzotta, Michael A Gatzoulis

Abstract read
In one paragraph

Article in International journal of cardiology. Congenital heart disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giulia IannacconeAdult Congenital Heart Diseases Unit, Royal Brompton Hospital, London, UK.
Francesca GrazianiDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario A, Gemelli IRCCS, Rome, Italy.
Polona KacarAdult Congenital Heart Diseases Unit, Royal Brompton Hospital, London, UK.
Pietro Paolo TamborrinoAdult Congenital Heart Diseases Unit, Royal Brompton Hospital, London, UK.
Rosa LilloDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Claudia MontanaroAdult Congenital Heart Diseases Unit, Royal Brompton Hospital, London, UK.
Francesco BurzottaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Michael A GatzoulisAdult Congenital Heart Diseases Unit, Royal Brompton Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripartum cardiomyopathy (PPCM) is a rare, but serious condition, with a non-negligible risk of adverse events. Several risk factors for PPCM have been individuated over the years, including Afro-American ethnicity, preeclampsia, advanced maternal age, genetic predisposition, multiparity, twin pregnancy, obesity, smoking and diabetes. However, PPCM pathophysiology is still poorly understood, thus making it challenging to develop disease specific therapies. At present, Bromocriptine is the only targeted drug, but further evidence is needed to establish indication and timing of administration. Therefore, these patients are mainly treated following general heart failure guidelines. Even though in most patients left ventricular ejection fraction recovers during follow-up, cases of persistent left ventricular dysfunction are not uncommon. Moreover, all patients detain a certain risk of recurrence after subsequent pregnancies, which is difficult to estimate due to the dearth of long-term prospective data. In this manuscript, we aim to provide an updated review of current evidence about PPCM pathophysiology, diagnosis, treatment and recurrence risk. In addition, we discuss the gaps in knowledge that should be addressed by future research.

Indexed as

Cardiovascular diseasePathophysiologyPeripartum cardiomyopathyPregnancyPrognosisSubsequent pregnancy

Identifiers

PMID39711771
PMCPMC11657248

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.