Evidence map›Paper›PMID 39712342›Full record

ArticleJournal of diabetes and metabolic disorders2025

Neonatal amino acid metabolism in gestational diabetes mellitus mothers treated with different treatment strategies.

Xinmei Zhu, Wenli Wang, Yuqi Yang, Hong Zhou, Wei Long, Bin Zhang

Abstract read
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Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinmei ZhuChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.
Wenli WangChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.
Yuqi YangChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.
Hong ZhouChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.
Wei LongChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.
Bin ZhangChangzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, 16 Dingxiang Road, Changzhou, 213000 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The changes in amino acid (AA) levels have been observed in pregnant women with gestational diabetes mellitus (GDM). However, it remains unclear whether the AA levels in offspring of GDM mothers are affected by GDM. This study aimed to investigate the changes in AA metabolism in offspring of pregnant women with GDM undergoing different glycemic control treatment regimens. Methods: 272 pregnant women treated at our hospital were selected and divided into the GDM and the non-GDM groups. The GDM group was further subdivided into three treatment groups: exercise-diet therapy, metformin therapy, and insulin therapy. The levels of 11 AAs of their offsprings were detected using tandem mass spectrometry and the differences in neonatal AA metabolism between the three treatment groups and the non-GDM group were compared. Results: There were significant differences in the levels of Arg, Cit, Met, Orn, and Pro of their offsprings between different treatment groups and the non-GDM group ( Conclusion: Regardless of the glycemic control treatment regimens used for GDM, AA metabolism related to the arginine family is influenced.

Indexed as

Amino acidDiabetes mellitusGestational diabetes mellitusNewborn

Identifiers

PMID39712342
PMCPMC11659532

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.