Evidence map›Paper›PMID 39714147›Full record

ArticleAntimicrobial agents and chemotherapy2025

Durlobactam in combination with β-lactams to combat

Eunjeong Shin, Khalid M Dousa, Magdalena A Taracila, Christopher R Bethel, Mary Nantongo, David C Nguyen, Chidiebere Akusobi, Sebastian G Kurz, Mark S Plummer, Charles L Daley and 6 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Journal of bacteriology · 2026
    Review
  5. The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Novel C5α-substituted carbapenems enhanceAntimicrobial agents and chemotherapy · 2025
    Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Eunjeong ShinLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.ORCID 0009-0006-2472-3264
Khalid M DousaLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.ORCID 0000-0003-3272-7231
Magdalena A TaracilaLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Christopher R BethelLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Mary NantongoDepartment of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
David C NguyenDivision of Infectious Diseases, Department of Pediatrics and Division of Infectious Diseases, and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0001-5738-2976
Chidiebere AkusobiDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Sebastian G KurzSchool of Medicine, Yale University, New Haven, Connecticut, USA.
Mark S PlummerBiopharmaworks, Groton, Connecticut, USA.
Charles L DaleyDivision of Mycobacterial and Respiratory Infections, National Jewish Health, Denver, Colorado, USA.
Steven M HollandLaboratory of Clinical Immunology and Microbiology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Eric J RubinDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-5120-962X
Jürgen B BulittaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, Florida, USA.
W Henry BoomDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Barry N KreiswirthCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.ORCID 0000-0002-0243-131X
Robert A BonomoLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.ORCID 0000-0002-3299-894X

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)D43TW010319 · FIC · CASE WESTERN RESERVE UNIVERSITY · PI BOOM, W. HENRY, JOLOBA, MOSES LUTAAKOME · 2016 to 2025
$3.1M
Cystic Fibrosis Foundation (CFF) SHIN24F0FIC NIH HHS D43 TW010319NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-Lactamase Inhibitorsbeta-LactamsImipenemMycobacterium abscessusMycobacterium Infections, NontuberculousAzabicyclo CompoundsDrug Therapy, CombinationMicrobial Sensitivity TestsPenicillin-Binding ProteinsPeptidyl TransferasesAzabicyclo Compoundsbeta-Lactamase Inhibitorsbeta-LactamsdurlobactamImipenemPenicillin-Binding ProteinsPeptidyl Transferasesbeta-lactamase inhibitorsbeta-lactamsMycobacterium abscessussynergistic bacterial killing

Identifiers

PMID39714147
PMCPMC11823594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.