ArticleAnesthesia and analgesia2025
Associations Between Social Determinants of Health and Opioid-Use Disorder Among Chronic Pain Patients From a Multi-Institutional Dataset.
Article in Anesthesia and analgesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Blunted light exposure amplitudes in patients with opioid use disorder.Npj biological timing and sleep · 2026Article
- Opioid use after breast cancer in Denmark: a nationwide study of social and clinical factors.Journal of the National Cancer Institute · 2026Article
- Social Determinants of Health Among Individuals Receiving Opioids for Pain Management.The Clinical journal of pain · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThis study examined the association between opioid-use disorder (OUD)-related diagnoses (eg, opioid dependence) and social determinants of health (SDoH) among patients with chronic pain.
methodsA cross-sectional study was performed using the All of Us dataset (including >70,000 patients) to measure associations between SDoH and OUD using population- and individual-level surveys. Mixed-effects multivariable regression models (random effect being zip code) were conducted for each of the key SDoH domains. The odds ratio (OR) and 95% confidence interval (CI) were reported.
resultsThere were 71,727 participants identified to have chronic pain, of which 7272 (10.1%) had OUD. Using data from all participants with population-level survey data available (n = 71,684), the Area Deprivation Index was associated with increased odds of OUD (OR, 5.70, 95% CI, 2.34-13.83, P < .001). Being unemployed (OR, 1.91, 95% CI, 1.59-2.31, P < .001) was associated with OUD. Chronic pain patients with a college degree or greater had lower odds of having OUD (OR, 0.48, 95% CI, 0.39-0.59, P < .001). Responses to questions related to delayed medical care (OR, 1.42, 95% CI, 1.20-1.69, P < .001) and inability to afford medical care (OR, 1.37, 95% CI, 1.16-1.63, P < .001) were associated with an increased odds of OUD. Chronic pain patients who were never married or without a partner (OR, 1.49, 95% CI, 1.28-1.73, P < .001) had higher odds of OUD.
conclusionsThe study revealed a significantly greater social disadvantage metric in chronic pain individuals with OUD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.