Evidence map›Paper›PMID 39715552›Full record

SynthesisJournal of medical Internet research2024

Machine Learning and Deep Learning for Diagnosis of Lumbar Spinal Stenosis: Systematic Review and Meta-Analysis.

Tianyi Wang, Ruiyuan Chen, Ning Fan, Lei Zang, Shuo Yuan, Peng Du, Qichao Wu, Aobo Wang, Jian Li, Xiaochuan Kong and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tianyi Wang *Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-5016-858X
Ruiyuan Chen *Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0009-0003-0745-4427
Ning Fan *Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0095-9476
Lei ZangBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-1403-4159
Shuo YuanBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-5668-9527
Peng DuBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-5017-8507
Qichao WuBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-6308-1774
Aobo WangBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-3271-1953
Jian LiBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-7726-6737
Xiaochuan KongBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-1385-3622
Wenyi ZhuBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-7336-9528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLumbar spinal stenosis (LSS) is a major cause of pain and disability in older individuals worldwide. Although increasing studies of traditional machine learning (TML) and deep learning (DL) were conducted in the field of diagnosing LSS and gained prominent results, the performance of these models has not been analyzed systematically.

objectiveThis systematic review and meta-analysis aimed to pool the results and evaluate the heterogeneity of the current studies in using TML or DL models to diagnose LSS, thereby providing more comprehensive information for further clinical application.

methodsThis review was performed under the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using articles extracted from PubMed, Embase databases, and Cochrane Library databases. Studies that evaluated DL or TML algorithms assessment value on diagnosing LSS were included, while those with duplicated or unavailable data were excluded. Quality Assessment of Diagnostic Accuracy Studies 2 was used to estimate the risk of bias in each study. The MIDAS module and the METAPROP module of Stata (StataCorp) were used for data synthesis and statistical analyses.

resultsA total of 12 studies with 15,044 patients reported the assessment value of TML or DL models for diagnosing LSS. The risk of bias assessment yielded 4 studies with high risk of bias, 3 with unclear risk of bias, and 5 with completely low risk of bias. The pooled sensitivity and specificity were 0.84 (95% CI: 0.82-0.86; I

conclusionsThis systematic review and meta-analysis emphasize that despite the generally satisfactory diagnostic performance of artificial intelligence systems in the experimental stage for the diagnosis of LSS, none of them is reliable and practical enough to apply in real clinical practice. Further efforts, including optimization of model balance, widely accepted objective reference standards, multimodal strategy, large dataset for training and testing, external validation, and sufficient and scientific report, should be made to bridge the distance between current TML or DL models and real-life clinical applications in future studies.

trial registrationPROSPERO CRD42024566535; https://tinyurl.com/msx59x8k.

Indexed as

Deep LearningMachine LearningSpinal StenosisHumansLumbar VertebraeAIartificial intelligencedeep learningdiagnosisdiagnosticearly detectionLSSlumbarlumbar spinal stenosismachine learningMLolder adultpredictive modelspine stenosis

Identifiers

PMID39715552
PMCPMC11704645

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.