Evidence mapPaperPMID 39717045Full record

ArticlePeerJ2024

Exploring the potential role of ENPP2 in polycystic ovary syndrome and endometrial cancer through bioinformatic analysis.

Xumin Zhang, Jianrong Liu, Chunmei Bai, Yang Li, Yanxin Fan

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xumin ZhangThe Fifth Clinical Medical College of Shanxi Medical University, TaiYuan, ShanXi, China.ORCID 0000-0002-8231-2600
Jianrong LiuThe Fifth Clinical Medical College of Shanxi Medical University, TaiYuan, ShanXi, China.ORCID 0000-0001-8163-7529
Chunmei BaiThe Fifth Clinical Medical College of Shanxi Medical University, TaiYuan, ShanXi, China.
Yang LiThe Fifth Clinical Medical College of Shanxi Medical University, TaiYuan, ShanXi, China.
Yanxin FanThe Fifth Clinical Medical College of Shanxi Medical University, TaiYuan, ShanXi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Growing evidence indicates a significant correlation between polycystic ovary syndrome (PCOS) and endometrial carcinoma (EC); nevertheless, the fundamental molecular mechanisms involved continue to be unclear. Methods: Initially, differential analysis, the least absolute shrinkage and selection operator (LASSO) regression, and support vector machine-recursive feature elimination (SVM-RFE) algorithms were employed to identify candidate genes associated with ferroptosis in PCOS. Subsequently, the TCGA-UCEC data were utilized to pinpoint the core gene. Then, the expression of Results: The datasets TCGA-UCEC (pertaining to EC), GSE34526, GSE137684, and GSE6798 (related to PCOS) were procured and subjected to analysis. The gene

Indexed as

Computational BiologyEndometrial NeoplasmsPhosphoric Diester HydrolasesPolycystic Ovary SyndromeCell Line, TumorDisease ProgressionFemaleGene Expression Regulation, NeoplasticGranulosa CellsHumansLysophospholipase DTumor MicroenvironmentLysophospholipase DPhosphoric Diester HydrolasesBioinformatic analysisEndometrial cancerENPP2FerroptosisPolycystic ovary syndrome

Identifiers

PMID39717045
PMCPMC11665432

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.