Evidence map›Paper›PMID 39717736›Full record

ArticleMetabolism open2024

Fish oil attenuates the expression of the CCL2 chemokine and histone-modifying enzymes in LPS-stimulated human preadipocytes.

Jussara de Jesus Simão, Andressa França de Sousa Bispo, Victor Tadeu Gonçalves Plata, Ana Beatriz Marques Abel, Monica Marques Telles, Lucia Maria Armelin-Correa, Maria Isabel Cardoso Alonso-Vale

Abstract read
In one paragraph

Article in Metabolism open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jussara de Jesus SimãoPost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.
Andressa França de Sousa BispoPost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.
Victor Tadeu Gonçalves PlataPost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.
Ana Beatriz Marques AbelPost-graduate Program in Nutrition -Paulista School of Medicine, Federal University of São Paulo - UNIFESP, Sao Paulo, Brazil.
Monica Marques TellesPost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.
Lucia Maria Armelin-CorreaPost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.
Maria Isabel Cardoso Alonso-ValePost-graduate Program in Chemical Biology - Institute of Environmental Sciences, Chemical and Pharmaceutical, Federal University of São Paulo - UNIFESP, Diadema, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In obesity, C-C chemokine ligand 2 (CCL2) plays a critical role in recruiting macrophages to white adipose tissue (WAT), contributing to chronic inflammation. In this study, we sought to explore the effects of fish oil (FO) on CCL2 expression and histone (H3K27)-modifying enzymes in both human model of preadipocytes and primary adipose-derived stem cells (ASCs). Present findings in preadipocytes lineage evidenced that lipopolysaccharide (LPS) increased

Indexed as

Adipose-derived mesenchymal stem cellsH3K27InflammationLipopolysaccharideMCP-1n-3 PUFA

Identifiers

PMID39717736
PMCPMC11665696

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.