Evidence map›Paper›PMID 39718205›Full record

ReviewRNA biology2025

The regulatory roles of RNA-binding proteins in the tumour immune microenvironment of gastrointestinal malignancies.

Dongqi Li, Xiangyu Chu, Weikang Liu, Yongsu Ma, Xiaodong Tian, Yinmo Yang

Abstract readReview
In one paragraph

Review in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongqi LiDepartment of Hepatobiliary and Pancreatic Surgery, Peking University First Hospital, Beijing, China.
Xiangyu ChuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Weikang LiuDepartment of Hepatobiliary and Pancreatic Surgery, Peking University First Hospital, Beijing, China.
Yongsu MaDepartment of Hepatobiliary and Pancreatic Surgery, Peking University First Hospital, Beijing, China.
Xiaodong TianDepartment of Hepatobiliary and Pancreatic Surgery, Peking University First Hospital, Beijing, China.
Yinmo YangDepartment of Hepatobiliary and Pancreatic Surgery, Peking University First Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The crosstalk between the tumour immune microenvironment (TIME) and tumour cells promote immune evasion and resistance to immunotherapy in gastrointestinal (GI) tumours. Post-transcriptional regulation of genes is pivotal to GI tumours progression, and RNA-binding proteins (RBPs) serve as key regulators via their RNA-binding domains. RBPs may exhibit either anti-tumour or pro-tumour functions by influencing the TIME through the modulation of mRNAs and non-coding RNAs expression, as well as post-transcriptional modifications, primarily N6-methyladenosine (m

Indexed as

Gastrointestinal NeoplasmsGene Expression Regulation, NeoplasticRNA-Binding ProteinsTumor MicroenvironmentAnimalsHumansRNA Processing, Post-TranscriptionalRNA-Binding ProteinsimmunotherapymRNAsncRNAsRNA binding proteintargeted therapytumour immune microenvironment

Identifiers

PMID39718205
PMCPMC12710923

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.