Evidence map›Paper›PMID 39719427›Full record

ReviewJournal of the American Heart Association2025

Mechanical Circulatory Support for Massive Pulmonary Embolism.

Salman Abdulaziz, Vivek Kakar, Praveen G Kumar, Ibrahim Fawzy Hassan, Alain Combes, Daniel Brodie, Nicholas A Barrett, Jack Tan, Saleh Fares Al Ali

Abstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Pulmonary embolism consensus.Archivos de cardiologia de Mexico · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salman AbdulazizDepartment of Health Abu Dhabi UAE.ORCID 0000-0001-5415-2008
Vivek KakarCleveland Clinic Abu Dhabi Abu Dhabi UAE.ORCID 0000-0001-6353-3283
Praveen G KumarCleveland Clinic Abu Dhabi Abu Dhabi UAE.
Ibrahim Fawzy HassanHamad Medical Corporation Doha Qatar.ORCID 0000-0002-0283-125X
Alain CombesPetie Salpetriere Hospital Sorbonne University Paris France.ORCID 0000-0002-6030-3957
Daniel BrodieThe John Hopkins University School of Medicine Baltimore Maryland USA.ORCID 0000-0002-0813-3145
Nicholas A BarrettGuy's and St Thomas' NHS Foundation Trust London UK.ORCID 0000-0002-4641-8192
Jack TanNational Heart Centre Singapore Singapore Singapore.ORCID 0000-0003-2181-4313
Saleh Fares Al AliDepartment of Health Abu Dhabi UAE.ORCID 0000-0001-9673-3548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the first hours of onset of symptoms, thus necessitating rapid evaluation and intervention. Venoarterial extracorporeal membrane oxygenation and other ventricular assist devices, depending on the hemodynamic derangements present, may be used to stabilize patients with massive PE refractory to initial therapies or with contraindications to other interventions. Given the abnormalities in both pulmonary circulation and gas exchange caused by massive PE, venoarterial extracorporeal membrane oxygenation may be considered the preferred form of mechanical circulatory support for most patients. Venoarterial extracorporeal membrane oxygenation unloads the right ventricle and improves oxygenation, which may not only help buy time until definitive treatment but may also reduce myocardial ischemia and myocardial dysfunction. This review summarizes the available clinical data on the use of mechanical circulatory support, especially venoarterial extracorporeal membrane oxygenation, in the treatment of patients with massive PE. Furthermore, this review also provides practical guidance on the implementation of this strategy in clinical practice.

Indexed as

Extracorporeal Membrane OxygenationPulmonary EmbolismHeart-Assist DevicesHemodynamicsHumansTreatment Outcomeextracorporeal membrane oxygenationintensive caremechanical circulatory supportpulmonary embolism

Identifiers

PMID39719427
PMCPMC12054433

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.