Evidence map›Paper›PMID 39719913›Full record

ArticleJoint diseases and related surgery2025

Sepsis predictors in earthquake survivors: A comparative analysis of amputation and fasciotomy patients.

Mustafa Comoglu, Güzelali Özdemir, Baran Sarıkaya, Fatih Acehan, Olgun Bingöl, Enver Kilic, Batuhan Bahadır, Mustafa Oruc, Burak Furkan Demir, Yusufcan Yılmaz and 1 more

Abstract readComparative Study
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Article in Joint diseases and related surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

11 authors.

Mustafa ComogluAnkara Bilkent Şehir Hastanesi İç Hastalıkları Kliniği, 06800 Çankaya, Ankara, Türkiye. comogludr@gmail.com.
Güzelali Özdemir
Baran Sarıkaya
Fatih Acehan
Olgun Bingöl
Enver Kilic
Batuhan Bahadır
Mustafa Oruc
Burak Furkan Demir
Yusufcan Yılmaz
Enes Seyda Sahiner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to identify predictors of sepsis in earthquake survivors who underwent either amputation or fasciotomy and to compare these two patient groups across many clinical outcomes, including sepsis. PATIENTS AND

methodsIn this retrospective study, a total of 1,608 patients who presented to our hospital following the February 6, 2023, Kahramanmaraş earthquakes were evaluated between February 2023 and March 2023. Of these, 138 patients (65 males, 73 females; median age: 35 years; range, 18 to 74 years) who underwent either fasciotomy or amputation were included in the study. Patients managed solely with fasciotomy were included in the fasciotomy group, while those who underwent amputation in at least one area were included in the amputation group. Sepsis predictors were investigated in this population. Additionally, the two groups were compared in terms of clinical outcomes, including bacteremia, sepsis, septic shock and mortality.

resultsOf the 138 earthquake survivors, 59 (42.8%) were in the amputation group, and 79 (57.2%) were in the fasciotomy group. There were no significant differences between the groups in terms of the development of crush syndrome or the need for renal replacement therapy (p=0.781 and p=0.411, respectively). The duration of entrapment under rubble was higher in the amputation group (p=0.030). While bacteremia was more common in the amputation group, there was no significant difference in relation to sepsis (p=0.002 and p=0.106, respectively). Septic shock and mortality rates were higher in the amputation group (p=0.001 and p=0.009, respectively). Multivariate analysis revealed that the number of traumatized sites (odds ratio [OR]=3.68, 95% confidence interval [CI]: 2.13-6.33, p<0.001), amputation at more than two sites (OR=4.27, 95% CI: 1.15-15.9, p=0.022), and fasciotomy at more than two sites (OR=2.71, 95% CI: 1.10-6.69, p=0.021) were significant predictors of sepsis.

conclusionPatients undergoing fasciotomy and amputation should be comprehensively evaluated for potential benefits and risks. Close monitoring for sepsis is particularly recommended for patients who have amputation or fasciotomy procedures at more than two sites.

Indexed as

Amputation, SurgicalEarthquakesFasciotomySepsisSurvivorsAdolescentAdultAgedFemaleHumansIndonesiaMaleMiddle AgedRetrospective StudiesRisk FactorsYoung Adult

Identifiers

PMID39719913
PMCPMC11734847

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