Evidence map›Paper›PMID 39720714›Full record

ArticleFrontiers in immunology2024

Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.

Elena Campione, Terenzio Cosio, Enrico Salvatore Pistoia, Fabio Artosi, Ruslana Gaeta Shumack, Cristiana Borselli, Antonia Rivieccio, Valerio Caputo, Marco Favaro, Roberto Sorge and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Microbial Biotransformation of Chicory byInternational journal of molecular sciences · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elena CampioneDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Terenzio CosioDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Enrico Salvatore PistoiaDepartment of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
Fabio ArtosiDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Ruslana Gaeta ShumackDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Cristiana BorselliDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Antonia RivieccioDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Valerio CaputoGenomic Medicine Laboratory UILDM, IRCCS Santa Lucia Foundation, Rome, Italy.
Marco FavaroDepartment of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
Roberto SorgeDepartment of Biostatistics, Tor Vergata University of Rome, Rome, Italy.
Francesca PicaDepartment of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
Luca BianchiDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Roberta GazianoDepartment of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fungi, including Methods: In this study, seventy patients with DDT psoriasis were enrolled to evaluate Results: In our population, 33 (47%) patients were colonized by Conclusions: Fungi may play a role in the psoriasis pathogenesis. Apremilast has been shown to ameliorate psoriasis signs and symptoms and counteract fungal overgrowth, probably by dampening inflammation, triggered by the fungal infections themselves. Thus, apremilast may represent an effective therapeutic approach in the treatment of DTT psoriasis and modulate the fungal colonization.

Indexed as

PsoriasisThalidomideAdultAgedAnti-Inflammatory Agents, Non-SteroidalCandidaCandidiasisCytokinesFemaleHumansMaleMiddle AgedPrevalenceTreatment OutcomeAnti-Inflammatory Agents, Non-SteroidalapremilastCytokinesThalidomideapremilastCandida speciescytokinesdifficult-to-treat psoriasis areasfungal infectionsIL-17

Identifiers

PMID39720714
PMCPMC11666449

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.