Evidence map›Paper›PMID 39721706›Full record

ArticleJournal of atherosclerosis and thrombosis2025

Prognostic Factors Associated with 2-year Mortality in Patients with Intermittent Claudication Treated with Endovascular Therapy for Femoropopliteal Lesions: Results from the Multicenter PROCYON Study.

Tatsuro Takei, Takahiro Tokuda, Naoki Yoshioka, Kenji Ogata, Akiko Tanaka, Shunsuke Kojima, Kohei Yamaguchi, Takashi Yanagiuchi, Tatsuya Nakama, LEADers PAD (peripheral artery disease) investigators

Abstract readMulticenter Study
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Validation of the European Society of Cardiology Ischemic and Bleeding Risk Criteria for Risk Stratification After Endovascular Therapy in Japanese Patients With Lower Extremity Artery Disease.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tatsuro TakeiDepartment of Cardiology, Tenyoukai Central Hospital.
Takahiro TokudaDepartment of Cardiology, Nagoya Heart Center.
Naoki YoshiokaDepartment of Cardiology, Ogaki Municipal Hospital.
Kenji OgataDepartment of Cardiology, Miyazaki Medical Association Hospital.
Akiko TanakaDepartment of Cardiology, Sendai Kousei Hospital.
Shunsuke KojimaDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center.
Kohei YamaguchiDepartment of Cardiology, Saiseikai Yokohama City Eastern Hospital.
Takashi YanagiuchiDepartment of Cardiology, Rakuwakai Otowa Hospital.
Tatsuya NakamaDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center.
LEADers PAD (peripheral artery disease) investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFew studies have evaluated the midterm prognosis of patients with intermittent claudication who underwent endovascular therapy (EVT) for femoropopliteal lesions. Therefore, we aimed to assess 2-year mortality and prognostic factors in these patients.

methodsWe retrospectively analyzed 947 patients who underwent EVT for intermittent claudication between January 2018 and December 2021 at eight Japanese cardiovascular centers. Kaplan-Meier survival analysis was performed for mortality, and prognostic factors were analyzed using the Cox proportional hazards regression model. Patient backgrounds and medications were included in the investigation of prognostic factors.

resultsNotably, 79 deaths occurred during the mean follow-up period of 20.9±6.2 months. The 2-year mortality rate was 9.1%. In multivariate analysis, body mass index (BMI) <18.5 kg/m

conclusionsDialysis, low BMI, CAD, and low ABI were risk factors for a worse 2-year prognosis in patients with intermittent claudication who underwent EVT for femoropopliteal lesions. Statins and cilostazol may improve the 2-year prognosis of patients with lower extremity artery disease.

Indexed as

Endovascular ProceduresFemoral ArteryIntermittent ClaudicationPeripheral Arterial DiseasePopliteal ArteryAgedAnkle Brachial IndexFemaleFollow-Up StudiesHumansJapanKaplan-Meier EstimateMaleMiddle AgedPrognosisRetrospective StudiesEndovascular therapyFemoropopliteal lesionIntermittent claudicationLower extremity artery diseasePrognosis

Identifiers

PMID39721706
PMCPMC12237783

What Socratic holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.