Trial reportObesity surgery2025
Effects of Sodium Bicarbonate Ringer's Solution Combined with Positive End-Expiratory Pressure on the Internal Environment of Patients Undergoing Bariatric Surgery: A Randomized 2 × 2 Factorial Design Pilot.
Trial report in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Effect of Bariatric Metabolic Surgery on the Incidence of Hypoglycemia for Obesity Patients.Obesity surgery · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the influence of sodium bicarbonate Ringer's solution (BRS) combined with positive end-expiratory pressure (PEEP) on the internal environment in patients who have undergone laparoscopic bariatric surgery.
methodsA total of 128 patients undergoing laparoscopic bariatric surgery were randomly divided into the control group (group C), the PEEP group (group P), the BRS group (group B), and the BRS combined with the PEEP group (group BP). The results of arterial blood gas analysis, including pH value, base excess (BE), concentrations of electrolyte, and lactate (Lac) were documented before intravenous infusion (T0) and 5 min after the surgery (T1). Additional metrics included tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) and were quantified before intravenous infusion and at 30 min post-surgery. The quality of recovery-15 questionnaire (QoR-15) scores were documented preoperatively (D0) and on the first (D1) and third (D3) days, postoperatively.
resultsThere was no significant interaction effect between the two factors of BRS and PEEP (p = 0.659). After the infusion of BRS, the pH level increased significantly at T2 (p < 0.05). Using PEEP during operation can increase PaO2 in patients with obesity (p < 0.05). The level of pH value is increased, and the concentrations of inflammatory factors are reduced due to the combination of BRS and PEEP (p < 0.05). Compared with group C, group BP exhibited an augmentation in QoR-15 (p < 0.05), and the recovery time of group BP was significantly shortened (p < 0.05).
conclusionsBRS combined with PEEP has been demonstrated to improve acid-base balance, reduce the inflammatory response, shorten the recovery time, and substantially enhance the quality of early postoperative recovery.
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