Evidence map›Paper›PMID 39725050›Full record

Observational studyThe journal of pain2025

Why is low educational attainment linked to worse pain and function in fibromyalgia?

Delia Fentazi, Bethany D Pester, Jolin B Yamin, Robert N Jamison, Robert R Edwards, Samantha M Meints

Abstract readObservational Study
In one paragraph

Observational study in The journal of pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Delia FentaziGraduate School of Medical Science, Boston University, Boston, MA, United States; Department of Anesthesiology, Perioperative and Pain Management, Brigham and Women's Hospital, Boston, MA, United States.
Bethany D PesterGraduate School of Medical Science, Boston University, Boston, MA, United States; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, United States.
Jolin B YaminDepartment of Anesthesiology, Perioperative and Pain Management, Brigham and Women's Hospital, Boston, MA, United States; Harvard University Medical School, Boston, MA, United States.
Robert N JamisonDepartment of Anesthesiology, Perioperative and Pain Management, Brigham and Women's Hospital, Boston, MA, United States; Harvard University Medical School, Boston, MA, United States.
Robert R EdwardsDepartment of Anesthesiology, Perioperative and Pain Management, Brigham and Women's Hospital, Boston, MA, United States; Harvard University Medical School, Boston, MA, United States.
Samantha M MeintsDepartment of Anesthesiology, Perioperative and Pain Management, Brigham and Women's Hospital, Boston, MA, United States; Harvard University Medical School, Boston, MA, United States. Electronic address: smeints@bwh.harvard.edu.

Funding

Brain Mechanisms Underlying CBT-Related Reductions in FibromyalgiaR01AR064367 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI EDWARDS, ROBERT R, NAPADOW, VITALY · 2014 to 2018
$4.0M
PREventing Pain after Surgery: A feasibility and acceptability study of Acceptance and Commitment Therapy for the prevention of chronic post surgical pain (PREPS)K23AR077088 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI MEINTS, SAMANTHA M · 2021 to 2025
$1.0M
Mentorship in Precision Pain Medicine via EPPIC-NETK24NS126570 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI EDWARDS, ROBERT R · 2021 to 2021
$319k
NIAMS NIH HHS K23 AR077088NIAMS NIH HHS R01 AR064367NINDS NIH HHS K24 NS126570
6 · The paper itself

Abstract

Lower educational attainment has been linked to worse pain in individuals with chronic pain, but the mechanisms of this relationship are not fully elucidated. This observational study analyzed the relationship between educational attainment and pain in patients with fibromyalgia (FM) and the potential psychological mechanisms driving this relationship. We hypothesized that (1) lower educational attainment would be associated with greater pain intensity and interference, and that (2) concerns about pain (CAP), anxiety, and depression would mediate the relationship between educational attainment and pain. A total of 119 adults (93.3% female, 79.7% White, Mage=50.4) with FM completed questionnaires including demographics, Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS), and Hospital Anxiety and Depression Scales (HADS). Pearson correlations and bootstrapped mediation analyses were conducted to examine the relationships among education, psychological variables, and pain variables. Education was inversely correlated with pain intensity and interference, CAP, anxiety, and depression (p<.05). CAP significantly mediated the relationship between education and pain intensity (95% CI [0.151, 0.026]), while both CAP and depression mediated the effects of education on pain interference (95% CI [0.195, -0.025]; 95% CI [-0.163, -0.004]). However, anxiety did not mediate either relationship. These findings suggest that greater CAP, and in part depression, may be possible mechanisms in the relationships between lower educational attainment and worse pain intensity and interference. This work has important implications in reducing pain disparities and provides direction for psychological treatment, suggesting that both depression and CAP may be critical targets especially for people with lower education attainment. PERSPECTIVES: This study examined the relationship between educational attainment, psychological variables, and pain. Results have implications for psychological intervention aimed at concerns about pain and depression, especially among individuals with low educational attainment.

Indexed as

AnxietyCatastrophizationChronic PainDepressionEducational StatusFibromyalgiaAdultFemaleHumansMaleMiddle AgedPain MeasurementDepressionEducationFibromyalgiaPain Concerns about painPain Intensity

Identifiers

PMID39725050
PMCPMC11807746

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.