Evidence map›Paper›PMID 39725719›Full record

SynthesisSleep & breathing = Schlaf & Atmung2024

Depressive symptoms after surgical and medical management of OSA: a systematic review and meta-analysis.

Alejandro R Marrero-Gonzalez, Craig D Salvador, Shaun A Nguyen, Ted A Meyer, Dee W Ford, Andrea M Rinn, Chitra Lal, Melissa Swanson, Mohamed Abdelwahab

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alejandro R Marrero-GonzalezSleep Surgery Division, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC550, Charleston, SC, 29425, USA.
Craig D SalvadorSleep Surgery Division, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC550, Charleston, SC, 29425, USA.
Shaun A NguyenSleep Surgery Division, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC550, Charleston, SC, 29425, USA.
Ted A MeyerSleep Surgery Division, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC550, Charleston, SC, 29425, USA.
Dee W FordDepartment of Pulmonary, Critical Care, Allergy, and Sleep, Medical University of South Carolina, Charleston, SC, USA.
Andrea M RinnDepartment of Pulmonary, Critical Care, Allergy, and Sleep, Medical University of South Carolina, Charleston, SC, USA.
Chitra LalDepartment of Pulmonary, Critical Care, Allergy, and Sleep, Medical University of South Carolina, Charleston, SC, USA.
Melissa SwansonExpertise Dental, Private Practice, Charleston, SC, USA.
Mohamed AbdelwahabSleep Surgery Division, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC550, Charleston, SC, 29425, USA. moa222@musc.edu.ORCID 0000-0002-2588-8355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effect of CPAP and surgical alternatives for OSA on depression and compare the results of surgery to CPAP. ​

methodsCOCHRANE Library, CINAHL, PubMed, and Scopus databases were searched for English-language articles. Meta-analysis of continuous measures (mean), proportions (%), and mean difference (Δ) with 95% confidence interval was conducted for objective and subjective outcomes before and after treatment with CPAP or surgical interventions.

resultsWe identified 2018 abstracts, 14 studies (N = 3,488) were included in the meta-analysis. Both treatments witnessed significant improvement in Apnea-hypopnea Index (AHI), with similar improvement with CPAP (Δ-48.8 [-51.2, -46.4]) and surgical interventions (Δ -20.22 [-31.3, -9.17]). An improvement in Epworth Sleepiness Scale (ESS) was noted between groups with (Δ -3.9 [-6.2, -1.6]) for the CPAP group and (Δ -4.3 [-6.0, -2.5]) for surgical interventions. The improvement of BDI II depression scores pre- and post-treatment was comparable between treatments with (Δ -4.1 [-5.8, -2.4]) for the CPAP group and (Δ- 5.6 [-9.2, -2.0]) for surgical interventions.

conclusionOur findings suggest a reduction in AHI is seen in both CPAP and surgical interventions for OSA, with no difference in AHI reduction between groups. Both treatments also lead to a similar improvement in depression scores providing strong evidence regards impact of surgery on OSA-associated mood disorders. While percent reduction in depression is higher in the surgical group, the difference did not reach statistical significance when compared to CPAP. When stratified by surgical intervention, most interventions suggest an improvement in depression scores.

Indexed as

Continuous Positive Airway PressureDepressionSleep Apnea, ObstructiveHumansCPAPDepressionOSASleep surgery

Identifiers

PMID39725719
PMCPMC11671573

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.