Evidence map›Paper›PMID 39725831›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2025

Pan-cancer and multiomics: advanced strategies for diagnosis, prognosis, and therapy in the complex genetic and molecular universe of cancer.

Camilly Victória Campanharo, Lívia Valle Dos Santos Silveira, Débora Dummer Meira, Matheus Correia Casotti, Lorena Souza Castro Altoé, Iúri Drumond Louro, André Felipe Monteiro Gonçalves, André Manhães Machado, Breno Sousa Paiva, Ester de Souza Inocencio and 12 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Camilly Victória CampanharoNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Lívia Valle Dos Santos SilveiraNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Débora Dummer MeiraNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil. debora.meira@ufes.br.
Matheus Correia CasottiNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Lorena Souza Castro AltoéNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Iúri Drumond LouroNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
André Felipe Monteiro GonçalvesNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
André Manhães MachadoNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Breno Sousa PaivaNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Ester de Souza InocencioNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Fabio Victor Vieira RochaNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Fellipe PesenteNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Giulia de Souza Cupertino de CastroNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
João Pedro Dos Santos da PaixãoNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
José Henrique Borges BourguignonNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Júlia Salarini CarneiroNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Juliana Ribeiro de OliveiraNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Pâmela de Souza FreireNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Sophia Bridi ZamprognoNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Taissa Dos Santos UchiyaNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Thais de Paula RezendeNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.
Vinícius de Pádua Sanders MedeirosNúcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Av. Fernando Ferrari, N. 514, Prédio Ciências Biológicas, Bloco A, Sala 106, Vitória, Espírito Santo, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pan-cancer and multi-omics approach is motivated by the genetic and molecular complexity inherent in the varied types of cancer. This method presents itself as a crucial resource for advancing early diagnosis, defining prognoses and identifying treatments that share common bases between different forms of tumors. The aim of this article is to explore pan-cancer analysis in conjunction with multi-omics strategies, evaluating laboratory, computational, clinical procedures and their consequences, as well as examining the tumor microenvironment, epigenetics and future directions of these technologies in patient management. To this end, a literature review was conducted using PUBMED, resulting in the selection of 260 articles, of which 81 were carefully chosen to support this analysis. The pan-cancer methodology is applied to the study of this microenvironment with the aim of investigating its common characteristics through multiomics data. The development of new therapies depends on understanding the oncogenic pathways associated with different cancers. Thus, the integration of multi-omics and pan-cancer analyzes offers an innovative perspective in the search for new control points, metabolic pathways and markers, in addition to facilitating the identification of patterns common to multiple cancer types, allowing the development of targeted treatments. In this way, the convergence of multiomics and clinical approaches promotes a broad view of cancer biology, leading to more effective and personalized therapies.

Indexed as

GenomicsNeoplasmsBiomarkers, TumorHumansMultiomicsPrognosisProteomicsTumor MicroenvironmentBiomarkers, TumorBiomarkersMulti-omicsPan-cancerTreatment

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.