Evidence map›Paper›PMID 39726056›Full record

ReviewTropical medicine and health2024

Plants used for the management of venereal diseases in sub-Saharan Africa: a systematic review and critical assessment of their research status.

Temitope O Omogbene, Ibraheem O Lawal, Stephen O Amoo, Anne A Adam, Fikisiwe C Gebashe, Adeyemi O Aremu

Abstract readReview
In one paragraph

Review in Tropical medicine and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Temitope O OmogbeneSchool of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, 4001, South Africa.
Ibraheem O LawalBiomedicinal Research Centre, Forestry Research Institute of Nigeria, Jericho Hill, P.M.B 5054, Ibadan, 200272, Nigeria.
Stephen O AmooAgricultural Research Council - Vegetables, Industrial and Medicinal Plants, Private Bag X293, Roodeplaat, Pretoria, 0001, South Africa.
Anne A AdamBiomedicinal Research Centre, Forestry Research Institute of Nigeria, Jericho Hill, P.M.B 5054, Ibadan, 200272, Nigeria.
Fikisiwe C GebasheSchool of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, 4001, South Africa.
Adeyemi O AremuSchool of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, 4001, South Africa. AremuA@ukzn.ac.za.ORCID http://orcid.org/0000-0002-6602-246X

Funding

National Research Foundation, South Africa KIC230820144560
6 · The paper itself

Abstract

backgroundSub-Saharan Africa faces one of the highest burdens of venereal diseases (VDs) globally. This review aims to critically evaluate the existing literature on the diverse Indigenous knowledge and medicinal plants utilised for treating VDs in sub-Saharan Africa.

methodsWe used the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol to guide the execution of the review. Relevant papers from scientific databases and search engines were assessed. The inclusion criteria included literature published from 2008 and May 16, 2024, and assessment of specific predetermined VDs. Medicinal plants based on certain ethnobotanical indices and data were recorded from each literature.

resultsAmong the 131 studies included in this review, a total of 20 relevant ethnobotanical reports were identified, with Nigeria and South Africa having the highest contributions (25% each). A high diversity and richness of 445 ethnobotanically valued anti-venereal plants (99 families) from over 872 Indigenous knowledge holders were inventoried. Plants with the highest diversity of use in traditional treatment of VDs are Cassia abbreviata, Ziziphus mucronata, Ximenia caffra, Catharanthus roseus, and Terminalia prunioides. The most represented families are Fabaceae (15.8%), Cucurbitaceae (5.9%), Solanaceae (5.9%), Euphorbiaceae (5%), and Combretaceae (5%). Roots and leaves were highly utilised with frequencies of 41.5% and 26.3%, respectively. The most used method of preparation are decoctions (36.7%) and infusions (12.2%), whereas oral route (72.9%) dominated the mode of administration of the medicinal plants.

conclusionsThis review consolidated data from sub-Saharan Africa-notwithstanding a limited number of studies in quantitative synthesis-and identified a diverse array of ethnobotanically valued anti-venereal plants, enabling meaningful conclusions to be drawn for future ethnopharmacological assessments. Effective plant conservation and advancement of ethnobotanical research in the region require stringent regulations and cross-country collaborations.

Indexed as

AntimicrobialBiodiversityEthnobotanyEthnopharmacologyIndigenous knowledgeSexually transmitted disease

Identifiers

PMID39726056
PMCPMC11670375

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.