Evidence map›Paper›PMID 39726261›Full record

ArticleAmerican journal of physiology. Cell physiology2025

Syntaxin 4-enhanced plasma membrane repair is independent of dysferlin in skeletal muscle.

Hsin-Yu Chen, Daniel E Michele

Abstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A role for theMolecular biology of the cell · 2026
    Article
  2. A role for thebioRxiv : the preprint server for biology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hsin-Yu ChenDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0001-7825-7891
Daniel E MicheleDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-4393-4551

Funding

Costamere Defects in Muscular DystrophiesR01AR049899 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI ERVASTI, JAMES M · 2005 to 2025
$8.2M
Mechanosignaling Functions of the Dystrophin Glycoprotein Complex in Muscular DystrophyR01AR068428 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MICHELE, DANIEL E · 2016 to 2020
$1.7M
In Vivo Molecular Probes for the Membrane Repair Pathway in MuscleR21AR066213 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MICHELE, DANIEL E · 2015 to 2016
$376k
HHS | National Institutes of Health (NIH) AR049899NIAMS NIH HHS R01 AR049899NIAMS NIH HHS R01 AR068428NIAMS NIH HHS R21 AR066213Rackham Graduate School
6 · The paper itself

Abstract

Plasma membrane repair (PMR) restores membrane integrity of cells, preventing cell death in vital organs, and has been studied extensively in skeletal muscle. Dysferlin, a sarcolemmal Ca

Indexed as

Cell MembraneDysferlinMuscle, SkeletalQa-SNARE ProteinsAnimalsHumansMaleMembrane FusionMiceMice, Inbred C57BLMuscle Fibers, SkeletalSNARE ProteinsDysferlinDysf protein, mouseQa-SNARE ProteinsSNARE Proteinsdysferlinmuscular dystrophyplasma membrane repairskeletal muscleSNAREs

Identifiers

PMID39726261
PMCPMC12235662

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.