Evidence map›Paper›PMID 39726815›Full record

ArticleBrain communications2025

Salivary oxytocin and amygdalar alterations in functional neurological disorders.

Samantha Weber, Natascha Stoffel, Juan Ansede-Bermejo, Raquel Cruz, Álvaro Del Real Bolt, Rupert Bruckmaier, Ángel Carracedo, Selma Aybek

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Imaging biomarkers in functional neurological disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samantha WeberDepartment of Neurology, Psychosomatic Medicine Unit, Inselspital Bern University Hospital, University of Bern, Bern 3012, Switzerland.ORCID https://orcid.org/0000-0002-2689-2938
Natascha StoffelDepartment of Neurology, Psychosomatic Medicine Unit, Inselspital Bern University Hospital, University of Bern, Bern 3012, Switzerland.
Juan Ansede-BermejoCentro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.
Raquel CruzCentro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.ORCID https://orcid.org/0000-0002-6964-8898
Álvaro Del Real BoltMedicine and Psychiatry Department, University of Cantabria, Santander 39005, Spain.
Rupert BruckmaierVeterinary Physiology, Vetsuisse Faculty, University of Bern, Bern 3012, Switzerland.
Ángel CarracedoCentro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, Santiago de Compostela 15706, Spain.
Selma AybekFaculty of Science and Medicine, University of Fribourg, Fribourg 1700, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals diagnosed with functional neurological disorder experience abnormal movement, gait, sensory processing or functional seizures, for which research into the pathophysiology identified psychosocial contributing factors as well as promising biomarkers. Recent pilot studies suggested that (epi-)genetic variants may act as vulnerability factors, for example, on the oxytocin pathway. This study set out to explore endogenous oxytocin hormone levels in saliva in a cohort of 59 functional neurological disorder patients and 65 healthy controls comparable in sex and age. First, we examined the association between salivary oxytocin levels with the genetic allelic variant (rs53576) of the oxytocin receptor gene (

Indexed as

amygdalaconversion disorderepigeneticsOXTRrs53576

Identifiers

PMID39726815
PMCPMC11670354

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.