Evidence mapPaperPMID 39726860Full record

ReviewFrontiers in physiology2024

Unraveling the complexity of the impact of physical exercise on male reproductive functions: a review of both sides of a coin.

Olayinka Emmanuel Adelowo, Blessing Monica Akindele, Cecilia Adedeji Adegbola, Precious Adeoye Oyedokun, Tunmise Maryanne Akhigbe, Roland Eghoghosoa Akhigbe

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olayinka Emmanuel AdelowoDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria.
Blessing Monica AkindeleDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria.
Cecilia Adedeji AdegbolaDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria.
Precious Adeoye OyedokunDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria.
Tunmise Maryanne AkhigbeReproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Nigeria.
Roland Eghoghosoa AkhigbeDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regular exercise is widely recognized for its numerous physical and mental benefits, but its effects on male reproductive health are less understood. This review aims to summarize the current evidence on the impact of exercise on male reproduction, including reproductive hormone regulation, spermatogenesis sperm quality, and fertility. Moderate exercise improves sperm quality, increasing count, motility, and morphology, while excessive and severe exercise may have detrimental effects. Exercise positively influences fertility by reducing oxidative stress and enhancing sperm DNA integrity. Regular physical activity regulates reproductive hormones, including testosterone, follicle-stimulating hormone, and luteinizing hormone. Exercise-induced weight management and improved insulin sensitivity also contribute to better reproductive health. In conclusion, exercise has a profound impact on male reproductive health, with moderate physical activity promoting improved hormonal balance, sperm quality, and fertility. However, severe/excessive exercise exerts negative effects. These findings imply that a balanced exercise routine, usually mild to moderate, combined with a healthy lifestyle is essential for optimal male reproductive health. However, once exercise is severe and prolonged, it could impair male reproductive health. Further research is needed to understand the mechanisms underlying the exercise-reproduction relationship fully.

Indexed as

cytokinesexerciseinflammationmale fertilityoxidative stressphysical activityspermatogenesistestosterone

Identifiers

PMID39726860
PMCPMC11669690

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.