ArticleCurrent medicinal chemistry2026
Post-COVID-19 Syndrome-associated Risk Factors for Acne Exacerbation.
Article in Current medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
introductionThis study aimed to investigate the impact of coronavirus disease 2019 (COVID-19) syndrome on various aspects of acne exacerbation. Additionally, we aimed to explore the risk factors for acne exacerbation after COVID-19 syndrome.
methodsA total of 211 subjects with acne were enrolled, and their key demographic characteristics and lifestyle factors were recorded. They were asked whether acne exacerbation occurred after COVID-19 syndrome, as well as the latency of exacerbation, the exacerbation location, and the form of skin lesions. The risk factors were analyzed using the Cox proportional hazard regression model. Overall, 41.2% of cases reported exacerbation of acne after COVID-19 syndrome. Age was found to be a protective factor. Additionally, sufficient fruit intake may slightly prevent exacerbation. For participants engaging in daily physical exercise, the likelihood of exacerbation was significantly increased after COVID-19 syndrome.
resultsThe probability of exacerbation was significantly higher if an acne itch was present. Patients who experienced exacerbation in the chin area were more likely to develop acne-induced anxiety. Males had a higher risk of aggravation of the cyst form. Interestingly, those with lower education levels were more likely to have aggravation in the right cheek after COVID-19 syndrome. Moreover, physical exercise might prevent aggravation in the front or back areas.
conclusionFinally, fish intake of ≥240 g per week was related to the aggravation of the hard nodule form. In conclusion, age and adequate fruit intake may play a protective role, while acne itch and daily exercise may be risk factors for acne exacerbation.
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