Evidence map›Paper›PMID 39728183›Full record

ReviewJournal of functional biomaterials2024

3D Bioprinting in Limb Salvage Surgery.

Iosif-Aliodor Timofticiuc, Serban Dragosloveanu, Ana Caruntu, Andreea-Elena Scheau, Ioana Anca Badarau, Nicolae Dragos Garofil, Andreea Cristiana Didilescu, Constantin Caruntu, Cristian Scheau

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Functional Biomaterials: Scaffolds for Innovative Treatments.Journal of functional biomaterials · 2025
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Iosif-Aliodor TimofticiucDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0002-3270-1488
Serban DragosloveanuDepartment of Orthopaedics and Traumatology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7403-1684
Ana CaruntuDepartment of Oral and Maxillofacial Surgery, "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0003-4200-3069
Andreea-Elena ScheauDepartment of Radiology and Medical Imaging, Fundeni Clinical Institute, 022328 Bucharest, Romania.ORCID 0000-0002-3360-2628
Ioana Anca BadarauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-7282-5189
Nicolae Dragos GarofilDepartment of General Surgery, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4693-2105
Andreea Cristiana DidilescuDepartment of Embryology and Microbiology, Faculty of Dentistry, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-2915-5124
Constantin CaruntuDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4530-7965
Cristian ScheauDepartment of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-7676-6393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of 3D bioprinting and the creation of innovative biocompatible materials, several new approaches have brought advantages to patients and surgical teams. Increasingly more bone defects are now treated using 3D-bioprinted prostheses and implementing new solutions relies on the ability of engineers and medical teams to identify methods of anchoring 3D-printed prostheses and to reveal the potential influence of bioactive materials on surrounding tissues. In this paper, we described why limb salvage surgery based on 3D bioprinting is a reliable and effective alternative to amputations, and why this approach is considered the new standard in modern medicine. The preliminary results of 3D bioprinting in one of the most challenging fields in surgery are promising for the future of machine-based medicine, but also for the possibility of replacing various parts from the human body with bioactive-based constructs. In addition, besides the materials and constructs that are already tested and applied in the human body, we also reviewed bioactive materials undergoing in vitro or in vivo testing with great potential for human applications in the near future. Also, we explored the recent advancements in clinically available 3D-bioprinted constructs and their relevance in this field.

Indexed as

3D bioprintingbiocompatibleelectron beam meltinglimb salvage surgeryprostheses

Identifiers

PMID39728183
PMCPMC11677104

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.