Evidence map›Paper›PMID 39728923›Full record

ArticleeLife2024

TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1α axis in melanoma.

Maojin Tian, Le Yang, Ziqian Zhao, Jigang Li, Lianqing Wang, Qingqing Yin, Wei Hu, Yunwei Lou, Jianxin Du, Peiqing Zhao

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maojin Tian *Center of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.ORCID https://orcid.org/0009-0004-9302-0162
Le Yang *Shandong First Medical University, Jinan, China.
Ziqian Zhao *The Second Medical College, Xinjiang Medical University, Urumqi, China.
Jigang LiCenter of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.
Lianqing WangCenter of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.
Qingqing YinShandong First Medical University, Jinan, China.
Wei HuCenter of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.
Yunwei LouSchool of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Jianxin DuCenter of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.
Peiqing ZhaoCenter of Translational Medicine, Zibo Central Hospital Affiliated to Binzhou Medical University, Zibo, China.ORCID https://orcid.org/0000-0002-9311-1927

Funding

Medicine and Health Science Technology Development Projects of Shandong Province 2018WS534Medicine and Health Science Technology Development Projects of Shandong Province 202102050803National Natural Science Foundation of China 12304241National Natural Science Foundation of China 81971491National Natural Science Foundation of China 81972002Natural Science Foundation of Shandong Province ZR2021MC083Natural Science Foundation of Shandong Province ZR2021MC165Natural Science Foundation of Shandong Province ZR2023MC136Natural Science Foundation of Shandong Province ZR2023QC168Natural Science Foundation of Shandong Province ZR2024MH175Taishan Young Scholar Foundation of Shandong Province tsqnz20231257Xinjiang Uygur Autonomous Region Training Program of Innovation and Entrepreneurship for College Students S202310760060
6 · The paper itself

Abstract

TIPE (

Indexed as

Carrier ProteinsGlycolysisHypoxia-Inducible Factor 1, alpha SubunitMelanomaMembrane ProteinsNeoplastic Stem CellsThyroid Hormone-Binding ProteinsAnimalsCell Line, TumorHumansMicePyruvate KinaseSignal TransductionThyroid HormonesCarrier ProteinsHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsPkm protein, mousePyruvate KinaseThyroid Hormone-Binding ProteinsThyroid Hormonescancer biologycell biologyglycolysisHIF-1αhumanmelanomamousePKM2TIPE

Identifiers

PMID39728923
PMCPMC11677236

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.