Evidence map›Paper›PMID 39729192›Full record

SynthesisEating and weight disorders : EWD2024

Eating disorders and disordered eating symptoms in individuals at clinical high risk for psychosis: a systematic review and meta-analysis.

Gabriele Lo Buglio, Marta Mirabella, Laura Muzi, Tommaso Boldrini, Erika Cerasti, Jone Bjornestad, Flavia Fiorentino, Andrea Polari, Eleonora Riccioli, Michele Angelo Rugo and 3 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gabriele Lo BuglioDepartment of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0003-2425-8383
Marta MirabellaDepartment of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-9720-3781
Laura MuziDepartment of Philosophy, Social Sciences, Humanities and Education, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0002-6394-6018
Tommaso BoldriniDepartment of Psychology and Educational Science, Pegaso Telematic University, Naples, Italy.ORCID http://orcid.org/0000-0003-3381-9445
Erika CerastiIo Se Posso Komunico, Rome, Italy.
Jone BjornestadDepartment of Social Studies, Faculty of Social Sciences, University of Stavanger, Stavanger, Norway.
Flavia FiorentinoDepartment of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID http://orcid.org/0009-0002-5954-1736
Andrea PolariOrygen Specialist Programs, Melbourne, Australia.ORCID http://orcid.org/0000-0002-0680-3192
Eleonora RiccioliDepartment of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Michele Angelo RugoEating Disorder Clinic "Residenza Gruber", Bologna, Italy.
Marco SolmiSCIENCES Lab, Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada.ORCID http://orcid.org/0000-0003-4877-7233
Vittorio Lingiardi *Department of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-1298-3935
Annalisa Tanzilli *Department of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy. annalisa.tanzilli@uniroma1.it.ORCID http://orcid.org/0000-0002-6098-2304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEating disorders (EDs) are among the least studied mental disorders in individuals at clinical high risk for psychosis (CHR-P). The primary aim (a) of this systematic review and meta-analysis was to identify factors predicting ED diagnoses in CHR-P individuals. The secondary aim (b) was providing a comprehensive clinical description of individuals with both CHR-P and EDs/ED-related symptoms.

methodsPreferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020-compliant systematic review and meta-analysis, searching PubMed/(EBSCO)PsycINFO/Web of Science for studies published between 01/01/2018 and 30/05/2023, including individuals with CHR-P and EDs/ED symptoms (PROSPERO CRD42023488792). Quality assessment was performed using the Newcastle-Ottawa Scale (NOS). We performed a meta-regression model on the proportion of EDs in CHR-P individuals (primary aim) and conducted a narrative synthesis (secondary aim).

resultsWe included 26 articles, reporting on 2,060 and 589 subjects for study aim (a) and (b), respectively (mean NOS score = 6.38). The prevalence of EDs in CHR-P individuals was 0.05 (95% CI 0.3-0.8). No factor had a significant effect on the proportion of EDs in CHR-P individuals. This result is limited by the inability to include ED-related symptoms and antipsychotic prescriptions in the meta-regression model, due to an insufficient number of studies reporting on these variables. The narrative synthesis offers a characterization of individuals with both CHR-P and ED/ED-related symptoms; however, the limited number of included studies is insufficient to support definitive conclusions.

conclusionsNo significant predictor of EDs was found in CHR-P individuals. Transdiagnostic, prospective cohort studies are warranted to examine long-term outcomes in individuals with both CHR-P and EDs, beyond diagnostic silos. LEVEL OF EVIDENCE: I. Systematic review and meta-analysis.

Indexed as

Feeding and Eating DisordersPsychotic DisordersHumansRisk FactorsClinical high risk for psychosisEating disordersMeta-analysisProdromePsychosisTransdiagnostic approach

Identifiers

PMID39729192
PMCPMC11680612

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.