Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities.

Sibel Özdaş, İpek Canatar, Gizem Ece Derici, Murat Koç

Abstract read

In one paragraph

Article in Journal of molecular histology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sibel ÖzdaşDepartment of Bioengineering, Adana Alparslan Türkeş Science and Technology University, Adana, Türkiye, Turkey. sozdas@atu.edu.tr.ORCID http://orcid.org/0000-0003-4610-2785

İpek CanatarDepartment of Bioengineering, Adana Alparslan Türkeş Science and Technology University, Adana, Türkiye, Turkey.ORCID http://orcid.org/0000-0001-9448-8112

Gizem Ece DericiDepartment of Bioengineering, Adana Alparslan Türkeş Science and Technology University, Adana, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-1557-7393

Murat KoçComplementary and Integrative Medicine, Department of Traditional, Ankara Yıldırım Beyazıt University, Ankara, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-0829-4571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is crucial to investigate new anti-diabetic agents and therapeutic approaches targeting molecules in potential signaling pathways for the treatment of Type 2 diabetes mellitus (T2DM). The objective of the study was to investigate the total phenolic content, antioxidant capacity, α-glucosidase, and α-amylase inhibitory activities of Bolanthus turcicus (B. turcicus), as well as their cytotoxic, anti-adipogenic, anti-diabetic, apoptotic, and anti-migration potential on adipocytes. B. turcicus samples were extracted with methanol (MeOH), ethyl acetate (EA) and aqueous (Aq) solvents. The MeOH extract had the highest phenolic content (81.14 mg GAE/g), followed by EA (74.93 mg GAE/g) and Aq (51.09 mg GAE/g). All extracts exhibited dose-dependent increases in α-glycosidase and α-amylase inhibitory activity. B. turcicus extracts showed cytotoxic effect on adipocytes with IC

Indexed as

AdipocytesAdipogenesisAntioxidantsHypoglycemic AgentsPlant Extracts3T3-L1 Cellsalpha-AmylasesAnimalsApoptosisAsteraceaeCell MovementDiabetes Mellitus, Type 2MicePhenolsalpha-AmylasesAntioxidantsHypoglycemic AgentsPhenolsPlant ExtractsAdipocytesAnti-adipogenicAnti-diabeticBolanthus turcicusCytotoxicDiabetes mellitus

Identifiers

PMID39729235

DOI10.3389/fphar.2019.00586

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.