Evidence mapPaperPMID 39730820Full record

Trial reportScientific reports2024

Evaluation of vascular photobiomodulation for orofacial pain and tension type headache following COVID 19 in a pragmatic randomized clinical trial.

Mayra Costanti Vilela Campos, Silvana Simões Velloso Schuler, Ana Julia Lacerda, Adriana Cátia Mazzoni, Tamiris Silva, Francine Cristina Silva Rosa, Manoela Domingues Martins, Kristianne Porta Santos Fernandes, Elsa Susana Fonseca, Raquel Agnelli Mesquita-Ferrari and 3 more

Abstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mayra Costanti Vilela CamposDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Silvana Simões Velloso SchulerDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Ana Julia LacerdaDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Adriana Cátia MazzoniDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Tamiris SilvaDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Francine Cristina Silva RosaMultidisciplinary Institute of Health, Federal University of Bahia, Vitória da Conquista, State of Bahia, Brazil.
Manoela Domingues MartinsOral Pathology and Oral Medicine, School of Dentistry, Federal University of Rio Grande Do Sul, Porto Alegre, State of Rio Grande Do Sul, Brazil.
Kristianne Porta Santos FernandesDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Elsa Susana FonsecaPhysics Department, University Beira Interior, 6201-001, Covilhã, Portugal.
Raquel Agnelli Mesquita-FerrariDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Anna Carolina Ratto Tempestini HorlianaDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Sandra Kalil BussadoriDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil.
Lara Jansiski MottaDepartment of Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, São Paulo, SP, 01525-000, Brazil. ljm.larajmotta@gmail.com.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.657920/2021-00
6 · The paper itself

Abstract

This pragmatic double-blind randomized clinical trial aims to assess the impact of vascular photobiomodulation on post-COVID-19 patients experiencing tension-type headache, orofacial pain, or both persisting for more than 3 months. Participants were divided into two groups: vascular photobiomodulation (VPBM) and simulated VPBM. Their conditions were evaluated using the Brief Pain Inventory (BPI), Visual Analogue Scale, and Headache Impact Test (HIT-6). Data analysis included both inter and intragroup assessments, employing per-protocol and intention-to-treat analyses. Significant differences were observed in pain levels pre- and post-treatment and between the two groups. These differences were evident in the average pain experienced in the previous week (p = 0.010) and various dimensions of the BPI questionnaire, such as the degree of pain interference with walking (p = 0.011), work (p = 0.009), sleep (p = 0.012), and enjoyment of life (p = 0.016). However, there was no statistically significant difference in headache impact on activities of daily living as measured by the HIT. Vascular photobiomodulation shows promise in reducing pain and enhancing the ability to engage in daily activities among post-COVID-19 patients experiencing persistent headaches and orofacial pain.

Indexed as

COVID-19Facial PainLow-Level Light TherapyTension-Type HeadacheAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedPain MeasurementSARS-CoV-2Treatment OutcomeCovid-19Facial painIntention to treat analysisPhotobiomodulationQuality of lifeTension-type headache

Identifiers

PMID39730820
PMCPMC11681234

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.