Evidence map›Paper›PMID 39731004›Full record

ArticleBMC anesthesiology2024

Association between the geriatric nutritional risk index and postoperative delirium in gastric surgery patients: an analysis of the MIMIC-IV database.

Yan Chen, Huangyi Chen, Yong Zhuang, Ying Wang, Zhisen Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yan Chen *Department of Anesthesiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Huangyi Chen *Department of Anesthesiology, Sun Yat-Sen University, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, Guangdong Province, China.
Yong ZhuangDepartment of Colorectal Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China.
Ying WangDepartment of Anesthesiology, Sun Yat-Sen University, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, Guangdong Province, China. wangy2369@mail.sysu.edu.cn.
Zhisen DaiDepartment of Anesthesiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian Province, China. daizhisen123@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explores the correlation between nutritional status, as determined by the Geriatric Nutritional Risk Index (GNRI), and the incidence of postoperative delirium (POD) in patients undergoing gastric surgery.

methodsData were obtained from the MIMIC-IV 2.2 database for patients aged 18 years or older who underwent gastric surgery. Patients were categorized into the malnourished group (GNRI < 98) and the non-malnourished group (GNRI ≥ 98). Multivariable logistic regression was performed to assess the association between GNRI and POD, and various potential confounders were adjusted to ensure the robustness of the results. Non-linear relationships between GNRI and POD risk were evaluated through restricted cubic spline (RCS) analysis. Subgroup analyses were conducted to examine the effect of GNRI on POD across different patient categories, and interactions were calculated. Propensity score matching (PSM) was employed to reduce confounding bias.

resultsThe study included a total of 4,818 patients, of whom 1,133 (23.5%) developed POD. Patients with a GNRI < 98 had a significantly higher risk of POD compared with those with a GNRI ≥ 98 (odds ratio (OR): 2.21, 95% confidence interval (CI): 1.93-2.53, p < 0.001). Even after adjustment for relevant confounders, GNRI remained significantly associated with POD (OR:1.24, 95% CI: 1.04-1.48, p < 0.001). This association was further supported by the results from PSM (OR:1.23, 95% CI: 1.01-1.51, p = 0.045). RCS analysis demonstrated a non-linear relationship between GNRI and POD risk (p < 0.05). Subgroup analyses revealed significant interactions within the cardiovascular disease, renal replacement therapy, benzodiazepine medication, and vasoactive drug subgroups (p for interaction < 0.05). After the patient population was adjusted to individuals aged 65 and older, this correlation remained significant (p for interaction < 0.05).

conclusionsThis study identifies a significant association between GNRI and the incidence of POD in patients undergoing gastric surgery. Improving nutritional status before surgery may lower the risk of developing POD.

Indexed as

Databases, FactualNutritional StatusPostoperative ComplicationsAgedAged, 80 and overDeliriumFemaleGeriatric AssessmentHumansIncidenceMaleMalnutritionMiddle AgedNutrition AssessmentRisk FactorsStomachGastric surgeryGNRIMIMIC-IV databaseNutritional statusPostoperative delirium

Identifiers

PMID39731004
PMCPMC11673328

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.