Evidence map›Paper›PMID 39732915›Full record

Trial reportScientific reports2024

Investigating the association between labor pain and cessation of breastfeeding.

Nadia Azlan Ayuby, Mei Qi Ang, Rehena Sultana, Chin Wen Tan, Ban Leong Sng

Registry-linked trialAbstract readClinical Trial, Phase IIClinical Trial, Phase IIIRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03167905 (Comparison of the Role of Epidural Analgesia Versus Non-epidural Analgesia in Postnatal Depression and Persistent Pain Development), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03167905 phase2 / phase3active not recruitingnot on this map

Comparison of the Role of Epidural Analgesia Versus Non-epidural Analgesia in Postnatal Depression and Persistent Pain Development: a Randomized Controlled Trial

TypeinterventionalSponsorKK Women's and Children's HospitalRan2017 to 2027Enrolled881ConditionsDepression, Postpartum, Analgesia, Obstetrical, Anesthesia, ObstetricalArmsEpidural delivery system, Entonox, Meperidine, Ultiva, Fentanyl
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadia Azlan AyubyDepartment of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.
Mei Qi AngDivision of Nursing, KK Women's and Children's Hospital, Singapore, Singapore.
Rehena SultanaCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Chin Wen TanDepartment of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore. tan.chin.wen@kkh.com.sg.
Ban Leong SngDepartment of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.

Funding

KKH Academic Medicine Research Start-Up Grant KKH-AM/2022/01National Medical Research Council (NRMC) Clinician Scientist award CSAINV16may004
6 · The paper itself

Abstract

Mothers encounter several challenges to sustain breastfeeding until the recommended 6 months of age. There is limited evidence on the impact of women's labor pain experiences upon cessation of breastfeeding. We aimed to investigate the association between women's labor pain experiences, intrapartum interventions, and pre-birth psychological vulnerabilities and cessation of breastfeeding. This was a secondary analysis of a clinical trial conducted in a tertiary hospital in Singapore between June 2017 and July 2021. Data were obtained from participants, electronic records and surveys administered before delivery, and postpartum 6-10 weeks. A total of 624 (76.8%) women were still breastfeeding at postpartum 6-10 weeks as compared to 189 (23.2%) that had discontinued breastfeeding. Multivariable regression analysis identified lower education level (aOR 3.88, 95% CI 2.57-5.85, p < 0.0001), having diabetes (aOR, 95% CI 1.21-5.44, p = 0.0141), presence of obstetric complications (aOR 1.57, 95% CI 1.00-2.46, p = 0.0494), artificial rupture of membrane (ARM) and oxytocin induction (aOR 2.07, 95% CI 1.22-3.50, p = 0.0068), lower age (aOR 0.92, 95% CI 0.88-0.97, p = 0.0010) and higher A-LPQ birth pain score (aOR 1.02, 95% CI 1.01-1.04, p = 0.0064) as independent associations with cessation of breastfeeding at postpartum 6-10 weeks, with AUC of the model being 0.72 (95% CI 0.68-0.77). Higher pain experienced during labor is associated with cessation of breastfeeding among several other intrapartum interventions and psychological vulnerabilities. Using risk stratification strategy, breastfeeding support services could be provided to women to optimize successful breastfeeding in the postpartum period.Trial registration: This study was registered on Clinicaltrials.gov NCT03167905 on 30/05/2017.

Indexed as

Breast FeedingLabor PainAdultFemaleHumansMothersPostpartum PeriodPregnancySingaporeBreastfeedingLabor onsetLabor painObstetrics

Identifiers

PMID39732915
PMCPMC11682455

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.