Evidence map›Paper›PMID 39733170›Full record

SynthesisSurgical endoscopy2025

Surgical management of complicated diverticulitis: systematic review and individual patient data network meta-analysis : An EAES/ESCP collaborative project.

Bright Huo, Monica Ortenzi, Roi Anteby, Yegor Tryliskyy, Francesco Maria Carrano, Georgios Seitidis, Dimitris Mavridis, Vincent T Hoek, Alberto Serventi, Willem A Bemelman and 17 more

Erratum issuedAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Utility of Colonoscopy After Acute Colonic Diverticulitis.Diagnostics (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Bright HuoDivision of General Surgery, Department of Surgery, McMaster University, Hamilton, Canada. brighthuo@dal.ca.ORCID 0000-0003-4999-4328
Monica OrtenziDepartment of General and Emergency Surgery, Polytechnic University of Marche, Ancona, Italy.
Roi AntebyDepartment of Surgery B, Sheba Medical Center, Tel Hashomer, Israel.
Yegor TryliskyyGreat Western Hospitals, NHS, Swindon, UK.
Francesco Maria CarranoDepartment of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, Rome, Italy.
Georgios SeitidisDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Dimitris MavridisDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Vincent T HoekDepartment of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands.
Alberto ServentiDepartment of Surgery, Ospedale Mons Galliano, Acqui Terme (AL), Italy.
Willem A BemelmanDepartment of Surgery, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Gian Andrea BindaDepartment of Surgery, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Rafael DuranDepartment of Radiology and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Triantafyllos DouliasDepartment of Colorectal Surgery, Colchester Hospital, East Suffolk and North Essex NHS Foundation Trust, Colchester, UK.
Nauzer ForbesDepartment of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Nader K FrancisThe Griffin Institute, Northwick Park and St Mark's Hospital, London, UK.
Fabian GrassDepartment of Visceral Surgery, Lausanne University Hospital CHUV, University of Lausanne (UNIL), Lausanne, Switzerland.
Jesper JensenPatient Partner, Copenhagen, Denmark.
Marianne KrogsgaardDepartment of Surgery, Zealand University Hospital, Koege, Denmark.
Lisa H MasseyDepartment of Colorectal Surgery, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Luca MorelliDivision of Translational and New Technologies in Medicine and Surgery, General Surgery Department, University of Pisa, Pisa, Italy.
Christian E OberkoflerSwiss HPB and Transplantation Center, Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.
Dorin E PopaDepartment of Surgery, Linköping University Hospital, Linköping, Sweden.
Johannes Kurt SchultzInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Shahnaz SultanDepartment of Medicine, Division of Gastroenterology, University of Minnesota, Minneapolis, MN, USA.
Jean-Jacques TuechDepartment of Digestive Surgery, Rouen University Hospital, 1 Rue de Germont, 76000, Rouen, France.
Hendrik Jaap BonjerCancer Center Amsterdam, Amsterdam, Netherlands.
Stavros A AntoniouDepartment of Surgery, Papageorgiou General Hospital, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe performed a systematic review and network meta-analysis (NMA) of individualized patient data (IPD) to inform the development of evidence-informed clinical practice recommendations.

methodsWe searched MEDLINE, Embase, and Cochrane Central in October 2023 to identify RCTs comparing Hartmann's resection (HR), primary resection and anastomosis (PRA), or laparoscopic peritoneal lavage (LPL) among patients with class Ib-IV Hinchey diverticulitis. Outcomes of interest were prioritized by an international, multidisciplinary panel including two patient partners. Article screening, data extraction for IPD, and risk of bias appraisal were performed by two reviewers. We used a random-effects NMA to synthesize direct and indirect evidence. Heterogeneity was evaluated using the I

resultsFourteen reports of seven RCTs were derived from 4,659 articles. IPD data were available for 595/678 patients (88.8%) across trials. Patients had a mean age ± SD of 64.61 ± 13.64 years and a mean BMI ± SD of 26.12 ± 5.20 kg/m

conclusionPRA likely confers a lower stoma rate at 1 year compared to HR, while there may be no difference in 30-day/in-hospital mortality. LPL likely confers a higher in-hospital/30-day mortality rate compared to HR and PRA.

Indexed as

ColectomyDiverticulitis, ColonicLaparoscopyAnastomosis, SurgicalHumansPeritoneal LavageRandomized Controlled Trials as TopicColorectal surgeryDiverticulitisGuidelinesLaparoscopic surgeryMinimally invasive surgery

Identifiers

PMID39733170

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.