Evidence map›Paper›PMID 39734451›Full record

ArticleWorld journal of gastrointestinal surgery2024

Zinc pretreatment for protection against intestinal ischemia-reperfusion injury.

Ming-Zhen Cheng, Jia-Hao Luo, Xin Li, Feng-Yong Liu, Wei-Jie Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming-Zhen ChengState Key Laboratory of Organ Failure Research, Department of General Surgery, Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Jia-Hao LuoState Key Laboratory of Organ Failure Research, Department of General Surgery, Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Xin LiDepartment of Interventional Radiology, The Fifth Medical Centre, Chinese PLA General Hospital, Beijing 100071, China.
Feng-Yong LiuDepartment of Interventional Radiology, Senior Department of Oncology, The Fifth Medical Centre, Chinese PLA General Hospital, Beijing 100071, China.
Wei-Jie ZhouState Key Laboratory of Organ Failure Research, Department of General Surgery, Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal Tumor, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China. weijiezhouum@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal ischemia

aimTo investigate the effects of zinc pretreatment on II/RI and associated multiorgan damage.

methodsC57BL/6 mice were pretreated with zinc sulfate (ZnSO

resultsZinc pretreatment significantly reduced intestinal damage in the SMAO and AAO models (

conclusionZinc pretreatment mitigates II/RI and reduces associated multiorgan damage. These findings suggest that zinc has potential clinical applications in protecting against I/R injuries.

Indexed as

Caco-2 cellsIntestinal ischemia-reperfusion injuryIntestinal organoidsOxidative stressReactive oxygen speciesZinc pretreatment

Identifiers

PMID39734451
PMCPMC11650234

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.