Evidence mapPaperPMID 39734765Full record

ReviewSAGE open medicine2024

Association between atherosclerosis and the development of multi-organ pathologies.

Siarhei A Dabravolski, Alexey V Churov, Natalia V Elizova, Alessio L Ravani, Amina E Karimova, Vasily N Sukhorukov, Alexander N Orekhov

Abstract readReview
In one paragraph

Review in SAGE open medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siarhei A DabravolskiDepartment of Biotechnology Engineering, Braude Academic College of Engineering, Karmiel, Israel.ORCID https://orcid.org/0000-0002-0547-6310
Alexey V ChurovInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Natalia V ElizovaInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Alessio L RavaniInstitute for Atherosclerosis Research, Moscow, Russia.
Amina E KarimovaFaculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia.
Vasily N SukhorukovInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Alexander N OrekhovInstitute of General Pathology and Pathophysiology, Moscow, Russia.ORCID https://orcid.org/0000-0002-6495-1628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a chronic inflammatory disease affecting the vascular system, characterised by the accumulation of modified lipoproteins, immune cell aggregation and the development of fibrous tissue within blood vessel walls. As atherosclerosis impacts blood vessels, its adverse effects may manifest across various tissues and organs. In this review, we examine the association of atherosclerosis with Alzheimer's disease, stroke, pancreatic and thyroid dysfunction, kidney stones and chronic kidney diseases. In several cases, the reciprocal causative effect of these diseases on the progression of atherosclerosis is also discussed. Particular attention is given to common risk factors, biomarkers and identified molecular mechanisms linking the pathophysiology of atherosclerosis to the dysfunction of multiple tissues and organs. Understanding the role of atherosclerosis and its associated microenvironmental conditions in the pathology of multi-organ disorders may unveil novel therapeutic avenues for the prevention and treatment of cardiovascular and associated diseases.

Indexed as

Alzheimer’s diseaseAtherosclerosischronic kidney diseasekidney stonesstrokethyroid dysfunction

Identifiers

PMID39734765
PMCPMC11672402

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.