Evidence map›Paper›PMID 39735125›Full record

ArticleCureus2024

The Prevalence of Vitamin B12 Deficiency Among Diabetic Patients Who Use Metformin.

Ahmad Aboshaiqah, Bader Aboshaiqah, Naif M Alharbi, Tariq I Almunyif, Saad D Binghanim, Abdullah K Almejalli

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Vitamin BFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmad AboshaiqahCollege of Nursing, King Saud University, Riyadh, SAU.
Bader AboshaiqahDepartment of Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.
Naif M AlharbiDepartment of Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh , SAU.
Tariq I AlmunyifDepartment of Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.
Saad D BinghanimDepartment of Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.
Abdullah K AlmejalliDepartment of Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimVitamin B12 deficiency is a recognized concern among patients with type 2 diabetes mellitus (T2DM) using metformin due to its potential impact on health outcomes. This study investigates the prevalence of vitamin B12 deficiency among diabetic patients using metformin at Dr. Sulaiman Al Habib Medical Group (HMG) hospitals.

methodsThis retrospective cohort study utilized electronic medical records from the VIDA system (www.cloudsolutions.com) over a one-year period. Participants included adult T2DM patients managed with metformin therapy. Data collection involved demographic details, medical history, medication usage, and serum vitamin B12 levels. Statistical analyses included descriptive statistics and comparative tests to assess deficiency prevalence across demographics.

resultsAmong the study population (N=37,781), vitamin B12 deficiency prevalence ranged from 460 (4.6%) to 507 (5.5%) across four quarters of 2023. Females exhibited a higher prevalence than males (P < 0.05), particularly in the second and fourth quarters. Age-related analyses identified younger and middle-aged groups (≤25 years and 36-45 years) as having higher deficiency rates (P < 0.001). Medication use, specifically metformin, correlated with increased deficiency prevalence (P < 0.001). DISCUSSION: The findings underscore the significance of gender, age, and medication use in influencing vitamin B12 status among diabetic patients using metformin. The study highlights the need for tailored monitoring strategies and interventions to mitigate deficiency risks and optimize patient outcomes. Future research should explore mechanisms underlying these associations and expand findings to broader populations.

conclusionThis study provides critical insights into the epidemiology of vitamin B12 deficiency among diabetic patients using metformin at HMG hospitals. The results emphasize the importance of personalized healthcare approaches to address nutrient deficiencies and improve overall patient care. This study summarizes the key elements of your research paper, focusing on the prevalence of vitamin B12 deficiency in relation to metformin use among diabetic patients.

Indexed as

diabetesmetforminprevalencetype 2 diabetesvitamin b12 deficiency

Identifiers

PMID39735125
PMCPMC11672162

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.