ReviewHeliyon2024
A comprehensive review on probiotics and their use in aquaculture: Biological control, efficacy, and safety through the genomics and wet methods.
Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The dual role of Actinobacteria in aquaculture: a systematic review of metabolic benefits and detrimental effects.Frontiers in microbiology · 2026Pooled it
- Mariculture Probiotics: A Scoping Review of Research Trends, Knowledge Gaps and Opportunities.Marine biotechnology (New York, N.Y.) · 2026Article
- Pathogenic mechanisms of Aeromonas hydrophila and the protective role of probiotics in sustainable aquaculture.Archives of microbiology · 2026Review
- Phenotypic and Genomic Characterization of Paenibacillus polymyxa SABE1 as a Probiotic Candidate in European Sea Bass (Dicentrarchus labrax).Probiotics and antimicrobial proteins · 2026Article
- DietaryMicroorganisms · 2026Article
- Comparative effects of viable and gamma-irradiated Bifidobacterium longum subsp. infantis on immune modulation and resistance to furunculosis in rainbow trout (Oncorhynchus mykiss).BMC microbiology · 2026Article
- Dietary Probiotics Modulate Oxidative Stress, Metabolic Status, and Immune-Related Gene Expression in Nile Tilapia (Veterinary sciences · 2026Article
- Genomic insights intoFrontiers in veterinary science · 2026Article
- PolyphasicFrontiers in nutrition · 2026Article
- Probiotics as eco-friendlybio-preservatives: In vivo mechanisms of mycotoxin inhibition and emerging applications for food safety and human health.Mycotoxin research · 2025Review
- Bacterial 16S Ribosomal Gene Fingerprints as a Tool to Diagnose and Mitigate Fish Larvae Gut Dysbiosis.Environmental microbiology reports · 2025Article
- Effect of Bacillus velezensis MT9 on Nile Tilapia (Oreochromis Niloticus) Intestinal Microbiota.Microbial ecology · 2025Article
- Review
- Modulation of Gut Microbiota, Intestinal Physiology, and Digestive Enzyme Levels by Duo-Strain Probiotics in African Catfish (Aquaculture nutrition · 2025Article
- Autophagy in aquatic animals: mechanisms, implications, and future directions.Frontiers in immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Probiotics, defined as viable microorganisms that enhance host health when consumed through the diet, exert their effects through mechanisms such as strengthening the immune system, enhancing resistance to infectious diseases, and improving tolerance to stressful conditions. Driven by a growing market, research on probiotics in aquaculture is a burgeoning field. However, the identification of new probiotics presents a complex challenge, necessitating careful consideration of both the safety and efficacy of the microorganisms employed. This review aims to delineate the most utilized and effective methods for identifying probiotics. The most effective approach currently combines in silico analysis of genomic sequences with in vitro and in vivo experiments. Two main categories of genetic traits are analyzed using bioinformatic tools: those that could harm the host or humans (e.g., toxin production, antibiotic resistance) and those that offer benefits (e.g., production of helpful compounds, and enzymes). Similarly, in vitro experiments allow us to examine the safety of a probiotic but also its effectiveness (e.g., ability to adhere to epithelia). Finally, in vivo experiments allow us to study the effect of probiotics on fish growth and health, including the ability of the probiotic to manipulate the host's microbiota and the ability to mitigate the infections. This review comprehensively analyzes these diverse aspects, with a particular focus on the potential of studying the interaction between bacterial pathogens and probiotics through these integrated methods.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.