Evidence map›Paper›PMID 39735922›Full record

ArticleJACS Au2024

Discovery of Spirosnuolides A-D, Type I/III Hybrid Polyketide Spiro-Macrolides for a Chemotherapeutic Lead against Lung Cancer.

Thanh-Hau Huynh, Sung Chul Jang, Yeon Hee Ban, Eun-Young Lee, Taeho Kim, Ilnam Kang, Joon Soo An, Sangwook Kang, Jaeho Han, Yun Kwon and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Isolation of Verrucosins A-E from a MarineJournal of natural products · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Thanh-Hau HuynhNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0009-0002-5789-6621
Sung Chul JangNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Yeon Hee BanDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Eun-Young LeeDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.
Taeho KimDivision of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Ilnam KangDepartment of Biological Sciences, Inha University, Incheon 22212, Republic of Korea.
Joon Soo AnNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-3282-5790
Sangwook KangNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0003-4866-9953
Jaeho HanNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Yun KwonResearch Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu 41566, Republic of Korea.
Daehyun OhResearch Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Hyeung-Geun ParkResearch Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-9645-8221
Jang-Cheon ChoDepartment of Biological Sciences, Inha University, Incheon 22212, Republic of Korea.
Jichan JangDivision of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Ki-Bong OhDepartment of Agricultural Biotechnology, College of Agriculture and Life Sciences and Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Sang-Jip NamDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.ORCID https://orcid.org/0000-0002-0944-6565
Sang Kook LeeNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-4306-7024
Dong-Chan OhNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0001-6405-5535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four new macrolides, spirosnuolides A-D (

Identifiers

PMID39735922
PMCPMC11672126

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.