Evidence mapPaperPMID 39736996Full record

ArticleFrontiers in microbiology2024

Whole-genome sequencing and genomic analysis of four

Wenjing Lu, Biqing Zha, Jie Lyu, Chenxi LingHu, Jing Chen, Sisi Deng, Xiangling Zhang, Liang Li, Guoqing Wang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenjing LuWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Biqing ZhaJiujiang Center for Disease Control and Prevention, Jiujiang, China.
Jie LyuMicrobiome Research and Application Center, BYHEALTH Institute of Nutrition and Health, Guangzhou, China.
Chenxi LingHuWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Jing ChenChengdu East New District Public Health Center, Chengdu, China.
Sisi DengHunan Provincial Center for Disease Control and Prevention, Changsha, China.
Xiangling ZhangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Liang LiMicrobiome Research and Application Center, BYHEALTH Institute of Nutrition and Health, Guangzhou, China.
Guoqing WangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Numerous studies have demonstrated that Methods: Based on this finding, we sequenced, assembled, and functionally annotated the whole genomes of four new human isolates from our laboratory: AKK-HX001, AKK-HX002, AKK-HX003, and AKK-HX004. Results: Phylogenetic analysis revealed that all four isolates belonged to the AmII phylogroup, whereas the type strain DSM 22959 is classified within the AmI phylogroup. Moreover, 2,184 shared homologous genes were identified among the four isolates. Functional annotation using the COG, KEGG, and CAZy databases indicated that the functional genes of the four isolates were primarily associated with metabolism. Two antibiotic resistance genes were identified in AKK-HX001 and AKK-HX002, while three resistance genes were detected in AKK-HX003 and AKK-HX004. Additionally, each of the four isolates possessed two virulence genes and three pathogenicity genes, none of which were associated with pathogenicity. The prediction of mobile genetic elements indicated unequal distributions of GIs among the isolates, and a complete CRISPR system was identified in all isolates except AKK-HX003. Two annotated regions of secondary metabolite biosynthesis genes, both belonging to Terpene, were detected using the antiSMASH online tool. Conclusion: These findings indicate that the four

Indexed as

Akkermansiagenomic analysisgenomic diversityprobioticswhole-genome sequencing

Identifiers

PMID39736996
PMCPMC11683593

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.