Evidence map›Paper›PMID 39737053›Full record

ArticleFrontiers in bioengineering and biotechnology2024

Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model.

Angelo Massaro, Cecilia Villegas Novoa, Yuli Wang, Nancy L Allbritton

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. AnBiofabrication · 2025
    Article
  5. Review
  6. A scalable long-termbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angelo MassaroDepartment of Bioengineering, University of Washington, Seattle, WA, United States.
Cecilia Villegas NovoaDepartment of Bioengineering, University of Washington, Seattle, WA, United States.
Yuli WangDepartment of Bioengineering, University of Washington, Seattle, WA, United States.
Nancy L AllbrittonDepartment of Bioengineering, University of Washington, Seattle, WA, United States.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Development of a microphysiologic system to assay the interaction of the human colonic epithelium on Clostridium difficileR01DK120606 · NIDDK · UNIVERSITY OF WASHINGTON · PI ALLBRITTON, NANCY L., SHEIKH, SHEHZAD Z. · 2020 to 2023
$2.2M
NCI NIH HHS P30 CA015704NIDDK NIH HHS R01 DK120606
6 · The paper itself

Abstract

Colonic epithelium is situated above a layer of fibroblasts that provide supportive factors for stem cells at the crypt base and promote differentiation of cells in the upper crypt and luminal surface. To study the fibroblast-epithelial cell interactions, an

Indexed as

colon cryptepithelial cellslarge intestinemicrophysiological systemorgan-on-chippericryptal fibroblasts

Identifiers

PMID39737053
PMCPMC11683563

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.