Evidence map›Paper›PMID 39737211›Full record

ArticleBioactive materials2025

Lipidomic analysis of plant-derived extracellular vesicles for guidance of potential anti-cancer therapy.

Fei Wang, Lanya Li, Junyao Deng, Jiacong Ai, Shushan Mo, Dandan Ding, Yingxian Xiao, Shiqi Hu, Dashuai Zhu, Qishan Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
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  5. Green nanomedicine for cancer therapy.Chinese medical journal · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fei WangThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Lanya LiThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Junyao DengThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Jiacong AiThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Shushan MoThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Dandan DingThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Yingxian XiaoThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Shiqi HuDepartment of Biomedical Engineering, Columbia University, 10032, New York, NY, USA.
Dashuai ZhuDepartment of Biomedical Engineering, Columbia University, 10032, New York, NY, USA.
Qishan LiThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Yan ZengThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.
Zhitong ChenInstitute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 518055, Shenzhen, China.
Ke ChengDepartment of Biomedical Engineering, Columbia University, 10032, New York, NY, USA.
Zhenhua LiThe Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), 523059, Dongguan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived extracellular vesicles (PEVs) have been regarded as a superior source for nanomedicine and drug delivery systems. Nevertheless, their clinical translation is hindered by the lack of clarity and even contradiction in their biomedical applications. Herein, we conducted a comprehensive compositional analysis of four commonly used PEVs to fully understand their functional lipid contents and assess their potential therapeutic applications. The lipidomic analysis revealed the presence of cytotoxic gingerols and shogaols in ginger-derived EVs (GEVs). Subsequent

Indexed as

anti-cancer therapyGingerLipidomic analysisPlant-derived extracellular vesiclesProtein markers

Identifiers

PMID39737211
PMCPMC11683192

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.