Evidence map›Paper›PMID 39737424›Full record

ArticleFrontiers in neurology2024

Vision transformer-equipped Convolutional Neural Networks for automated Alzheimer's disease diagnosis using 3D MRI scans.

Zhen Zhao, Pauline Shan Qing Yeoh, Xiaowei Zuo, Joon Huang Chuah, Chee-Onn Chow, Xiang Wu, Khin Wee Lai

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhen ZhaoDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Pauline Shan Qing YeohDepartment of Biomedical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Xiaowei ZuoDepartment of Psychiatry, The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Joon Huang ChuahDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Chee-Onn ChowDepartment of Electrical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Xiang WuSchool of Medical Information Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Khin Wee LaiDepartment of Biomedical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative ailment that is becoming increasingly common, making it a major worldwide health concern. Effective care depends on an early and correct diagnosis, but traditional diagnostic techniques are frequently constrained by subjectivity and expensive costs. This study proposes a novel Vision Transformer-equipped Convolutional Neural Networks (VECNN) that uses three-dimensional magnetic resonance imaging to improve diagnosis accuracy. Utilizing the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset, which comprised 2,248 3D MRI images and diverse patient demographics, the proposed model achieved an accuracy of 92.14%, a precision of 86.84%, a sensitivity of 93.27%, and a specificity of 89.95% in distinguishing between AD, healthy controls (HC), and moderate cognitive impairment (MCI). The findings suggest that VECNN can be a valuable tool in clinical settings, providing a non-invasive, cost-effective, and objective diagnostic technique. This research opens the door for future advancements in early diagnosis and personalized therapy for Alzheimer's Disease.

Indexed as

Alzheimer's diseaseclassificationConvolutional Neural Networkmagnetic resonance imagingtransformer

Identifiers

PMID39737424
PMCPMC11682981

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.