Evidence map›Paper›PMID 39738288›Full record

ArticleScientific reports2024

Engagement in moderate-intensity physical activity supports overnight memory retention in older adults.

Miranda G Chappel-Farley, Destiny E Berisha, Abhishek Dave, Rachel M Sanders, Christopher E Kline, John T Janecek, Negin Sattari, Kitty K Lui, Ivy Y Chen, Ariel B Neikrug and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Miranda G Chappel-FarleyDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, USA. chappelfarleymg@upmc.edu.
Destiny E BerishaDepartment of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Abhishek DaveDepartment of Cognitive Sciences, University of California Irvine, Irvine, CA, 92697, USA.
Rachel M SandersDepartment of Health and Human Development, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Christopher E KlineDepartment of Health and Human Development, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
John T JanecekDepartment of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Negin SattariDepartment of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Kitty K LuiJoint Doctoral Program in Clinical Psychology, San Diego State University, University of California San Diego, San Diego, CA, 92093, USA.
Ivy Y ChenDepartment of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Ariel B NeikrugDepartment of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Ruth M BencaCenter for the Neurobiology of Learning and Memory, University of California Irvine, Irvine, CA, 92697, USA.
Michael A YassaDepartment of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Bryce A ManderDepartment of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.

Funding

Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
Training Program in Learning and MemoryT32MH119049 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BRUCE L MCNAUGHTON, Manuella Yassa · 2019 to 2026
$1.4M
Relationships between local and global mechanisms of sleep apnea, Alzheimer's disease biomarkers, and memory impairment in cognitively asymptomatic older adultsK01AG068353 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MANDER, BRYCE A. · 2020 to 2024
$636k
Circuit-specific tau burden and mechanisms of sleep-dependent memory processing in older adults at risk for Alzheimer’s diseaseR21AG079552 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MANDER, BRYCE A., YASSA, MICHAEL A · 2022 to 2022
$432k
Neurobiological mechanisms of sleep and exercise effects on memory in older adults at risk for Alzheimer's diseaseF31AG074703 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHAPPEL-FARLEY, MIRANDA · 2021 to 2023
$111k
Cerebrovascular and neurophysiological mechanisms of sleep-dependent memory impairment in older adults at risk for Alzheimer's diseaseF31AG084308 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI BERISHA, DESTINY · 2024 to 2025
$82k
American Academy of Sleep Medicine Strategic AwardNHLBI NIH HHS T32 HL082610NHLBI NIH HHS T32HL082610NIA NIH HHS F31 AG074703NIA NIH HHS F31AG074703NIA NIH HHS F31 AG084308NIA NIH HHS F31AG084308NIA NIH HHS K01 AG068353NIA NIH HHS R21AG07955NIA NIH HHS R21 AG079552NIMH NIH HHS T32 MH119049
6 · The paper itself

Abstract

Preserving the ability to vividly recall emotionally rich experiences contributes to quality of life in older adulthood. While prior works suggest that moderate-intensity physical activity (MPA) may bolster memory, it is unclear whether this extends to emotionally salient memories consolidated during sleep. In the current study, older adults (mean age = 72.3 ± 5.8) completed an overnight polysomnography assessment with emotional memory tested before and after sleep and a self-report questionnaire assessing habitual PA. Results show that better negative emotional memory consolidation was associated with the frequency and duration of MPA. Statistically replacing 30 min of lower-intensity activity with MPA was associated with better negative emotional memory consolidation. MPA may enhance sleep-dependent consolidation of negative memories in older adults, with modest increases in MPA yielding significant consolidation benefits. Findings may guide interventions and inform public health recommendations by demonstrating that substituting even short durations of low-intensity activity for MPA could produce significant cognitive gains in older adulthood.

Indexed as

ExerciseAgedAged, 80 and overEmotionsFemaleHumansMaleMemoryMemory ConsolidationMental RecallPolysomnographyQuality of LifeSleepSurveys and Questionnaires

Identifiers

PMID39738288
PMCPMC11686232

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.