ArticleJournal of assisted reproduction and genetics2025
Optimal embryo management strategies for patients undergoing antagonist protocols in IVF treatment.
Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence of pregnancy outcomes among patients with recurrent implantation failure: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Development and validation of machine learning models for predicting blastocyst yield in IVF cycles.Scientific reports · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSelection of optimal embryo transfer strategies for IVF patients treated with antagonist protocols.
methodsA retrospective study was conducted to assess whether whole embryo culture to the blastocyst stage could enhance the cumulative live birth rate (CLBR). The study included data from the first oocyte retrieval cycle of 4131 patients who underwent IVF treatment between January 2018 and June 2022. Patients were categorized into two strategies based on whether they underwent partial blastocyst culture (PBC) or whole embryo culture (WEC), and were further subdivided into three subgroups according to the number of high-quality embryos on Day 3: 0-2 embryos (subgroup 1), 3-7 embryos (subgroup 2), and 8 or more embryos (subgroup 3). Propensity score matching was used to perform a 1:1 match for patients across the three subgroups. The primary outcome measure was the CLBR per oocyte retrieval cycle.
resultsAfter propensity score matching, there were no statistically significant differences in the baseline data among patients across the three corresponding subgroups for the PBC and WEC strategies. The analysis of CLBR in single oocyte retrieval cycles revealed that subgroup 1 had a significantly higher rate with the PBC strategy compared to the WEC strategy (33.0% vs. 25.7%, P = 0.018). In subgroups 2 and 3, there were no statistically significant differences in the CLBR between patients using the two embryo management strategies.
conclusionsWhen patients have 0-2 high-quality embryos on Day 3, opting for Day 3 embryo transfer rather than blastocyst culture can increase the chances of embryo transfer and improve the CLBR.
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Registered trials
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