Evidence map›Paper›PMID 39739936›Full record

ArticleThe Kaohsiung journal of medical sciences2025

Curcumin-induced exosomal FTO from bone marrow stem cells alleviates sepsis-associated acute kidney injury by modulating the m6A methylation of OXSR1.

Ting Yang, Hui Yu, Zheng Xie

Abstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ting YangDepartment of Emergency Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.
Hui YuDepartment of Emergency Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.ORCID https://orcid.org/0009-0001-9252-2812
Zheng XieDepartment of Emergency Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin and bone marrow stem cells (BMSCs)-derived exosomes are considered to be useful for the treatment of many human diseases, including sepsis-associated acute kidney injury (SA-AKI). However, the role and underlying molecular mechanism of curcumin-loaded BMSCs-derived exosomes in the progression of SA-AKI remain unclear. Exosomes (BMSCs-EXO

Indexed as

Acute Kidney InjuryAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOBone Marrow CellsCurcuminExosomesMesenchymal Stem CellsSepsisAnimalsApoptosisCell LineCell ProliferationHumansLipopolysaccharidesMaleMethylationAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOCurcuminFTO protein, humanLipopolysaccharidesN-methyladenosinebone marrow stem cellsexosomesFTOOXSR1sepsis‐associated AKI

Identifiers

PMID39739936
PMCPMC11827542

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.