Evidence map›Paper›PMID 39742007›Full record

ReviewCardiovascular therapeutics2024

Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi.

Chenggang Xu, Le Tang, Lixin Hu, Yunzhe Huang, Jin Tang, Xiaohu Wang, Feng Wang

Abstract readReview
In one paragraph

Review in Cardiovascular therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenggang XuDepartment of Cardiology XuanCheng City Central Hospital, Xuancheng, China.ORCID https://orcid.org/0009-0005-0419-7087
Le TangPharmacology College Anhui Xinhua University, Hefei, China.ORCID https://orcid.org/0009-0001-9281-4057
Lixin HuDepartment of Pharmaceutics China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0009-0006-1591-7200
Yunzhe HuangGraduate School Wannan Medical College, Wuhu, China.ORCID https://orcid.org/0000-0002-7427-3998
Jin TangGraduate School Wannan Medical College, Wuhu, China.ORCID https://orcid.org/0000-0002-6070-7302
Xiaohu WangDepartment of Pharmaceutics China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0003-2005-0614
Feng WangDepartment of Cardiology XuanCheng City Central Hospital, Xuancheng, China.ORCID https://orcid.org/0009-0001-7914-5469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-inflammatory, and cardiovascular protective effects. In recent years, benzoylaconine has garnered significant attention in basic research on heart diseases, emerging as a focal point of investigation. This paper presents a comprehensive review of the pharmacological effects of benzoylaconine, alongside an overview of advancements in metabolic characterization. The objective is to furnish valuable insights that can serve as a cornerstone for further exploration, utilization, and advancement of benzoylaconine in pharmacological research.

Indexed as

Cardiovascular DiseasesDrugs, Chinese HerbalAconitineAnimalsCardiovascular AgentsDiterpenesHumansSignal TransductionAconitinebenzoylaconineCardiovascular AgentsDiterpenesDrugs, Chinese Herbalfuzi drug herbalanti-inflammationbenzoylaconinecardiac diseasespharmacokineticspharmacological effects

Identifiers

PMID39742007
PMCPMC11236470

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.