Inverted U-Shaped Association of Soluble Transferrin Receptor Concentrations with Risks of Cardiovascular Diseases in Overweight Individuals: A Cross-Sectional Study.

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Article in Reviews in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Xiao HuDepartment of Cardiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, 223300 Huaian, Jiangsu, China.ORCID https://orcid.org/0000-0002-4412-641X

Jing XuDepartment of Respiratory and Critical Care Medicine, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, 223300 Huaian, Jiangsu, China.

Yang GuDepartment of Cardiology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, 223300 Huaian, Jiangsu, China.ORCID https://orcid.org/0009-0008-0018-5208

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Iron metabolism may play a role in cardiovascular disease (CVD) pathogenesis. The association between iron metabolism and CVD has yet to be fully investigated. This study evaluated whether iron metabolism was associated with CVD risk and whether the body mass index (BMI) of US adults varied the association. Methods: A cross-sectional study was performed using the National Health and Nutrition Examination Survey (NHANES), conducted from 2017 to 2018. Generalized additive models (GAMs) and multivariable logistic regression were adopted to analyze the association between iron metabolism (serum iron (SI), serum ferritin (SF), transferrin saturation (TSAT), and soluble transferrin receptor (sTfR)) and CVD risk. Further, stratified analysis was conducted to identify patients with high CVD risk. Results: Participants with CVD tended to have significantly increased levels of sTfR ( Conclusions: Increased sTfR levels were non-linearly related to the CVD risk in the overweight population.

Indexed as

cardiovascular diseaseNational Health and Nutrition Examination Surveyoverweightsoluble transferrin receptor

Identifiers

PMID39742215

DOI10.31083/j.rcm2512439

PMCPMC11683708

What Socratic holds

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.