Evidence map›Paper›PMID 39742242›Full record

ReviewReviews in cardiovascular medicine2024

Plaque Stabilization and Regression, from Mechanisms to Surveillance and Clinical Strategies.

Xi Zhang, Huanhuan Feng, Yan Han, Xiaohang Yuan, Mengting Jiang, Wei Wang, Lei Gao

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xi ZhangSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.
Huanhuan FengMedical School of Chinese PLA, 100853 Beijing, China.
Yan HanSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.
Xiaohang YuanSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.
Mengting JiangSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.
Wei WangSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.
Lei GaoSenior Department of Cardiology, Sixth Medical Center of Chinese PLA General Hospital, 100853 Beijing, China.ORCID https://orcid.org/0000-0001-9539-9293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With advances in therapies to reduce cardiovascular events and improvements in coronary imaging, an increasing number of clinical trials have demonstrated that treatments to reduce cardiovascular events in coronary artery disease are associated with favorable effects on atherosclerotic plaque size and characteristics. It has been observed that various drugs may induce plaque regression and enhance plaque stability after plaque formation. Numerous clinical trials have been conducted to verify the occurrence of plaque stabilization and regression and their beneficial effects on cardiovascular events. Using invasive imaging techniques such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT), researchers have been able to gather evidence supporting the existence of coronary plaque stabilization and regression. In this review, we explore the possible mechanisms of plaque stabilization and regression, summarize the imaging features of plaque stabilization and regression, and assemble the evidence from clinical studies that have used different features as observational endpoints.

Indexed as

atheroscleroticintravascular ultrasoundlipid-lowing therapyoptical coherence tomographyplaque regressionplaque stabilization

Identifiers

PMID39742242
PMCPMC11683705

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.