Evidence map›Paper›PMID 39744684›Full record

ArticleTheranostics2025

Detecting metastatic potential of cancer through longitudinal vasculature imaging of biomaterial scaffold using non-invasive

Zhanpeng Xu, Guillermo Escalona, Ian Schrack, Wei Zhang, Tianqu Zhai, Lonnie D Shea, Xueding Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhanpeng XuDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Guillermo EscalonaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Ian SchrackDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Wei ZhangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Tianqu ZhaiDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Lonnie D SheaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Xueding WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Physiology of Inflammatory Arthritis in High ResolutionR01AR060350 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, XUEDING · 2011 to 2021
$6.0M
Personalized Cancer Therapy Guided by Photoacoustic Chemical Imaging (PACI) of Tumor Microenvironment (TME)R01CA250499 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KLEER, CELINA G, WANG, XUEDING · 2020 to 2025
$3.1M
Multimodal Molecular Imaging of Choroidal NeovascularizationR01EY034325 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yannis Mantas Paulus, XUEDING WANG · 2023 to 2026
$2.5M
Identifying intercellular circuits driving cell phenotypes within a nicheR01CA243916 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JERUSS, JACQUELINE SARA, SHEA, LONNIE D · 2019 to 2023
$2.3M
Tissue engineering tools for monitoring the cellular and molecular response to therapyR01CA272940 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACQUELINE SARA JERUSS, Lonnie D Shea · 2023 to 2026
$1.7M
NCI NIH HHS R01 CA243916NCI NIH HHS R01 CA250499NCI NIH HHS R01 CA272940NEI NIH HHS R01 EY034325NIAMS NIH HHS R01 AR060350
6 · The paper itself

Abstract

Metastasis represents a stage in which the therapeutic objective changes from curing disease to prolonging survival, as detection typically occurs at advanced stages. Technologies for the early identification of disease would enable treatment at a lower disease burden and heterogeneity. Herein, we investigate the vascular dynamics within a synthetic metastatic niche as a potential marker of disease progression.

Indexed as

Photoacoustic TechniquesTomography, Optical CoherenceTriple Negative Breast NeoplasmsAnimalsBiocompatible MaterialsCell Line, TumorFemaleHumansMiceMice, Inbred BALB CMicroscopyNeoplasm MetastasisNeovascularization, PathologicTissue ScaffoldsBiocompatible MaterialsAngiogenesisBiomaterial scaffoldBreast cancerMetastatic progressionOptical coherence tomographyPhotoacoustic microscopyVascularization

Identifiers

PMID39744684
PMCPMC11671391

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.